Immunohistochemical Distribituon of COX-1, COX-2, and TGF beta-1 in the Duodenum of Rats Treated with Capsaicin

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dc.authorid0000-0002-5703-2164
dc.authorscopusid37121662100
dc.authorscopusid34971025700
dc.authorscopusid27667663200
dc.authorscopusid57188626782
dc.authorscopusid6603667446
dc.authorwosidbakır, buket/ABA-8248-2020
dc.authorwosidAsker, Hasan/A-5543-2018
dc.contributor.authorBakır, Buket
dc.contributor.authorEliş Yıldız, Sevda
dc.contributor.authorKaradağ Sarı, Ebru
dc.contributor.authorAsker, Hasan
dc.contributor.authorNazli, Mumtaz
dc.date.accessioned2022-05-11T14:42:27Z
dc.date.available2022-05-11T14:42:27Z
dc.date.issued2016
dc.departmentFakülteler, Veteriner Fakültesi, Temel Bilimler Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı
dc.description.abstractThe purpose of this study was to investigate the effects of capsaicin on the duodenal distribution of cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and Transforming growth factor beta-1 (TGF beta-1) in rats. Rats were divided into two groups (n = 10 in each group). Experimental group treated with capsaicin (1 mg/kg, subcutaneously) was injected in 10% ethanol, 1% Tween and 80% distilled water everyday for a period of one week and in not injected control group. Localisations of COX-1, COX-2 and TGF beta-1 were observed in villus and crypt ephitelial cells, and smooth muscle cells. In conclusion, in this study, capsaicin administration was found to increase the release of COX-1 and COX-2, and TGF beta-1.
dc.identifier.doi10.9775/kvfd.2015.14559
dc.identifier.endpage338
dc.identifier.issn1300-6045
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84961960524
dc.identifier.scopusqualityQ3
dc.identifier.startpage333
dc.identifier.urihttps://doi.org/10.9775/kvfd.2015.14559
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9383
dc.identifier.volume22
dc.identifier.wosWOS:000374312100003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorBakır, Buket
dc.language.isoen
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisi
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCapsaicin
dc.subjectCyclooxygenase
dc.subjectDuodenum
dc.subjectTransforming growth factor beta-1
dc.subjectGrowth-Factor-Alpha
dc.subjectEpithelial-Cells
dc.subjectFactor-Beta
dc.subjectCyclooxygenase 2
dc.subjectGene-Expression
dc.subjectPain Management
dc.subjectSmall-Intestine
dc.subjectMessenger-Rna
dc.subjectReceptor
dc.subjectMice
dc.titleImmunohistochemical Distribituon of COX-1, COX-2, and TGF beta-1 in the Duodenum of Rats Treated with Capsaicin
dc.title.alternativeCapsaicin uygulanan sıçanların duodenumda COX-1, COX-2 ve TGF?-1'in immünohistokimyasal dağılımı]
dc.typeArticle

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