Treatment with Melatonin Enhances the Embryo Quality and the Development of Vitrified/warmed Eight Cell Mouse Embryos by Solid Surface Vitrification (SSV)

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dc.authorscopusid57223956195
dc.authorscopusid57209266981
dc.authorscopusid41862429400
dc.authorscopusid6603553213
dc.contributor.authorÇağlar, Kübra
dc.contributor.authorKocabay, A.
dc.contributor.authorTaşkın, Ali Cihan
dc.contributor.authorArat, Sezen
dc.date.accessioned2022-05-11T14:10:24Z
dc.date.available2022-05-11T14:10:24Z
dc.date.issued2020
dc.departmentFakülteler, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümü
dc.departmentEnstitüler, Fen Bilimleri Enstitüsü, Tarımsal Biyoteknoloji Ana Bilim Dalı
dc.description.abstractBACKGROUND: Melatonin is an endocrine hormone secreted from the pineal gland located outside the blood-brain barrier. OBJECTIVE: In this study, in vitro propagated eight-cell mouse embryos were vitrified by the Solid Surface Vitrification (SSV) method and after thawing, their in vitro development and embryo qualities in melatonin added media were investigated. METHODS: Pronuclear stage embryos obtained from super ovulated B6CBAF1/J strain mice, were cultured until the eight-cell stage. Then these eight-cell embryos were vitrified by the SSV method and after thawing, cultured in melatonin added media at 37°C and 5 %CO2 conditions until the blastocyst stage. RESULT: In the experimental period, in vitro embryo development rates of the control, SSV and +10-12 M melatonin groups were observed as 97%, 86% and 93%, respectively. CONCLUSION: Our results indicated that melatonin addition slightly increased the development rates and total cell numbers of embryos vitrified by the SSV method.
dc.identifier.endpage67
dc.identifier.issn0143-2044
dc.identifier.issue2en_US
dc.identifier.pmid33988655
dc.identifier.scopus2-s2.0-85106554057
dc.identifier.scopusqualityQ3
dc.identifier.startpage62
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5390
dc.identifier.volume41
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇağlar, Kübra
dc.institutionauthorArat, Sezen
dc.language.isoen
dc.publisherNLM (Medline)
dc.relation.ispartofCryo letters
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectmelatonin
dc.subjectanimal
dc.subjectblastocyst
dc.subjectcryopreservation
dc.subjectmammalian embryo
dc.subjectmouse
dc.subjectvitrification
dc.subjectAnimals
dc.subjectBlastocyst
dc.subjectCryopreservation
dc.subjectEmbryo, Mammalian
dc.subjectMelatonin
dc.subjectMice
dc.subjectVitrification
dc.titleTreatment with Melatonin Enhances the Embryo Quality and the Development of Vitrified/warmed Eight Cell Mouse Embryos by Solid Surface Vitrification (SSV)
dc.typeArticle

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