Antioxidant, antimicrobial activities and total flavonoid contents of Cirsium bulgaricum DC. leaf extracts

dc.authorid0000-0003-2759-4411
dc.authorid0000-0002-7706-5801
dc.authorscopusid55235059200
dc.authorscopusid23979419500
dc.authorscopusid56685922800
dc.authorscopusid33367486100
dc.authorwosidkarasakal, ayca/ABA-4762-2020
dc.authorwosidDemirci, Ahmet Şükrü/AAT-6596-2020
dc.authorwosidCabi, Evren/H-2263-2019
dc.contributor.authorKarasakal, Ayça
dc.contributor.authorDemirci, Ahmet Şükrü
dc.contributor.authorDemirok, Nazan Tokatlı
dc.contributor.authorCabi, Evren
dc.date.accessioned2022-05-11T14:07:38Z
dc.date.available2022-05-11T14:07:38Z
dc.date.issued2015
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümü
dc.departmentFakülteler, Ziraat Fakültesi, Gıda Mühendisliği Bölümü
dc.departmentEnstitüler, Sağlık Bilimleri Enstitüsü, Beslenme ve Diyetetik Ana Bilim Dalı
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Biyoloji Bölümü
dc.description.abstractIn this study, the antioxidant activities of methanol and acetone extracts of Cirsium bulgaricum DC. (Asteraceae) were evaluated by five antioxidant assays, including phosphomolybdate method, cupric ion reducing capacity (CUPRAC), 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonicacid)/persulfate) ABTS/Persulfate, N,N-dimethyl-pphenylenediamine (DMPD) and a Ce(IV)-based reducing capacity (CERAC) methods. The 80% methanol and acetone extracts showed 0.005-6.16 +/- 0.03 mmol/g and 0.004-5.02 +/- 0.02 [(trolox (TR), catechin (CT), epicatechin (EC), rutin (RT), quercetin (QR), naringin (NG) in CUPRAC and ABTS/Persulfate methods, respectively]. According to DMPD methods, inhibition effect were showed 2.3%+/- 0.02 for 80% methanol and 4.6%+/- 0.07 for acetone. Ascorbic acid equivalent mmol (AA)/g extract in CERAC method was found to be 0.0834 +/- 0.09 for 80% methanol and 0.5622 +/- 0.05 for acetone. Ascorbic acid equivalent mu g ascorbic acid (AA) / mL extract were found 807.6 +/- 0.07 for 80% methanol and 292.4 +/- 0.01 for acetone in phpsphomolybdate method. In the addition to the antioxidant activity of the extract, the total flavonoid content was measured. Total flavonoid content of 80% methanol and acetone extracts was found to be 105.5-645 +/- 0.04 mu g/ml quercetin and rutin equivalent. For the determination of antibacterial activities Escherichia coli (E. coli) ATCC 25922, Escherichia coli(E. coli) O157:H7 ATCC 33150, Salmonella Enteritidis(S. Enteritidis) ATCC 1 3 0 7 6, Listeria monocytogenes(L. monocytogenes) ATCC 7 6 4 4, Staphylococcus aureus(S. aureus) ATCC 25923 bacteria were used as test bacteria. Acetone extracts showed antibacterial activity against all of the tested bacteria ranged between 17.00 +/- 1.72-19.88 +/- 1.75 mm and 80% methanol extracts showed antibacterial activity against all of the tested bacteria ranged between 11.35 +/- 1.43-14.43 +/- 1.32 mm.
dc.identifier.endpage51
dc.identifier.issn1309-0801
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84931049131
dc.identifier.scopusqualityN/A
dc.identifier.startpage43
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5161
dc.identifier.volume19
dc.identifier.wosWOS:000361222600006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorKarasakal, Ayça
dc.institutionauthorDemirci, Ahmet Şükrü
dc.institutionauthorDemirok, Nazan Tokatlı
dc.institutionauthorCabi, Evren
dc.language.isoen
dc.publisherMarmara Univ, Fac Pharmacy
dc.relation.ispartofMarmara Pharmaceutical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntioxidant Activity
dc.subjectAntimicrobial Activity
dc.subjectTotal Flavonoid Contents
dc.subjectCirsium bulgaricum
dc.subjectPhenolic Composition
dc.subjectCapacity
dc.subjectFruits
dc.subjectTea
dc.subjectVegetables
dc.subjectAnatolia
dc.subjectCuprac
dc.subjectRegion
dc.subjectAssay
dc.titleAntioxidant, antimicrobial activities and total flavonoid contents of Cirsium bulgaricum DC. leaf extracts
dc.title.alternativeCirsium bulgaricum yaprak ekstresinin antioksidan, antimikrobiyal etkinliği ve toplam flavonoid içeriği]
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
5161.pdf
Boyut:
271.31 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text