The relationship between the levels of the fluoride ion and the thyroid hormones in goats with fluorosis

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dc.authorscopusid35725134000
dc.authorscopusid6701387212
dc.contributor.authorArslan, Sezai
dc.contributor.authorKeleş, İhsan
dc.date.accessioned2022-05-11T14:42:17Z
dc.date.available2022-05-11T14:42:17Z
dc.date.issued2017
dc.departmentFakülteler, Veteriner Fakültesi, Klinik Bilimler Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractIn the present study, 104 goats with endemic fluorosis, living at the foot of the mountains Ağrı (Mount Ararat) and Tendürek, were compared with 30 healthy goats to investigate the relationship between the plasma levels of the fluoride ion (F) and the thyroid hormones. In addition to the 104 goats with fluorosis all having dental fluorosis, 1.92% had exostoses in their palpable bones, 19.23% had mastication difficulties with weight loss, 2.88% had nail deformities, and 7.69% had lameness. However, signs of goitre in their necks were not present on inspection and palpation. The plasma F concentration was significantly higher (p<0.001) in the fluorosis group compared to the control group. The plasma F concentrations tended to be higher in the older animals compared to the younger animals, but not significantly so. Compared to the control group, the serum total thyroxine (TT4) was significantly reduced (p<0.01) in the fluorosis group. No significant differences between the fluorosis and the control groups were found for the serum concentrations of total triiodotyronine (TT3), free triiodotyronine (FT3), or free thyroxine (FT4). Significant decreases were present in the levels of TT3(p<0.01) and FT4(p<0.001) in the older goats with fluorosis, 3–5-years-old and >5-years-old, compared to the younger animals, aged 1–<3 years. © 2017, ISFR.
dc.identifier.endpage142
dc.identifier.issn0015-4725
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85026430300
dc.identifier.scopusqualityQ3
dc.identifier.startpage135
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9316
dc.identifier.volume50
dc.indekslendigikaynakScopus
dc.institutionauthorArslan, Sezai
dc.language.isoen
dc.publisherInternational Society for Fluoride Research
dc.relation.ispartofFluoride
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectFluoride
dc.subjectFluorosis
dc.subjectGoats
dc.subjectGoitre
dc.subjectThyroid hormones
dc.subjectfluoride ion
dc.subjectthyroid hormone
dc.subjectthyronine
dc.subjectthyroxine
dc.subjectanimal experiment
dc.subjectanimal lameness
dc.subjectArticle
dc.subjectchild
dc.subjectcontrolled study
dc.subjectfluorosis
dc.subjectgoat
dc.subjectmastication
dc.subjectnail disease
dc.subjectnonhuman
dc.subjectthyroxine blood level
dc.subjectweight reduction
dc.titleThe relationship between the levels of the fluoride ion and the thyroid hormones in goats with fluorosis
dc.typeArticle

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