Protective Role of Vitamin C on Sperm Characteristics and Testicular Damage in Rats Exposed to Radiation

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dc.authorid0000-0002-1693-6378
dc.authorid0000-0002-0187-2615
dc.authorid0000-0002-5143-7208
dc.authorscopusid12753984100
dc.authorscopusid6504697876
dc.authorscopusid24279870800
dc.authorscopusid6602186020
dc.authorscopusid6505557944
dc.authorscopusid55910059600
dc.authorscopusid55318019500
dc.authorwosidSeker, Ugur/A-7403-2014
dc.authorwosidCirit, Ümüt/AAG-5572-2019
dc.authorwosidDenli, Muzaffer/W-1181-2017
dc.authorwosidözkan, oktay/W-3511-2017
dc.authorwosidTaş, Muzaffer/AAG-4752-2019
dc.contributor.authorTaş, Muzaffer
dc.contributor.authorCirit, Ümüt
dc.contributor.authorÖzkan, Oktay
dc.contributor.authorDenli, Muzaffer
dc.contributor.authorZincircioğlu, Seyit Burhanedtin
dc.contributor.authorŞeker, Uğur
dc.contributor.authorEren, Leyla Bilge
dc.date.accessioned2022-05-11T14:42:15Z
dc.date.available2022-05-11T14:42:15Z
dc.date.issued2014
dc.departmentFakülteler, Veteriner Fakültesi, Klinik Bilimler Bölümü, Dölerme ve Suni Tohumlama Ana Bilim Dalı
dc.description.abstractThe aim of this study was to investigate the protective effects of vitamin C on sperm characteristics and testes in male rats exposed gamma radiation (2 Gy). A total of 21 adult male wistar albino rats (8 weeks of age, weighing 180-220 g) were divided into three groups. Control, radiotherapy (received scrotal.-radiation of 2 Gy as a single dose) and radiotherapy + vitamin C treated rats (during the 55 days after irradiation, 500 mg vitamin C/500 ml water daily orally). Testes samples from all groups were taken at day 55 post-irradiation and epididymal sperm characteristics, all-genital organs weights and testes histology were evaluated. Radiotherapy decreased significantly the sperm motility, concentration, left testes and epididymis weights, Johnsen's biopsy score and seminiferous tubular diameter but it increased the sperm head defects as compared to the Control group (P<0.05). The administration of vitamin C only reduced the harmful effects of radiotherapy on the seminiferous tubular diameter (P<0.05). It has been concluded that the radiotherapy may cause alteration in the genital organ weights, spermatologic and hystologic parameters in rats and administration of vitamin C may be slightly beneficial for seminiferous tubular diameter following testicular irradiation during the radiotherapy.
dc.identifier.doi10.9775/kvfd.2013.9445
dc.identifier.endpage64
dc.identifier.issn1300-6045
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84887269924
dc.identifier.scopusqualityQ3
dc.identifier.startpage59
dc.identifier.urihttps://doi.org/10.9775/kvfd.2013.9445
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9300
dc.identifier.volume20
dc.identifier.wosWOS:000328083200009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorTaş, Muzaffer
dc.language.isoen
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisi
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectRadiation
dc.subjectVitamin C
dc.subjectSperm
dc.subjectTestes
dc.subjectRat
dc.subjectAntioxidant Activity
dc.subjectCells
dc.subjectIrradiation
dc.subjectAcid
dc.titleProtective Role of Vitamin C on Sperm Characteristics and Testicular Damage in Rats Exposed to Radiation
dc.title.alternativeRadyasyona maruz bi{dotless}raki{dotless}lmi{dotless}ş si{dotless}çanlarda spermatozoa özellikleri ve testislerde yaratti{dotless}?i{dotless} hasar üzerine vitamin C'nin koruyucu rolü]
dc.typeArticle

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