Biological activity of new flavonoids and phenolic compounds from Cirsium italicum (Savi) DC.

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dc.authorid0000-0001-8108-5509
dc.authorid0000-0003-4384-4265
dc.authorid0000-0001-6356-0898
dc.authorscopusid6505866652
dc.authorscopusid57196417867
dc.authorscopusid56634751100
dc.authorscopusid57196417785
dc.authorwosidorak, hulya/ABA-6973-2020
dc.authorwosidOZER, Merve/AAC-7839-2020
dc.authorwosidSABUDAK, Temine/AAG-6784-2019
dc.contributor.authorŞabudak, Temine
dc.contributor.authorÇalışkan, Hilmican
dc.contributor.authorOrak, Hakime Hülya
dc.contributor.authorÖzer, Merve
dc.date.accessioned2022-05-11T14:15:37Z
dc.date.available2022-05-11T14:15:37Z
dc.date.issued2021
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümü
dc.departmentMeslek Yüksekokulları, Teknik Bilimler Meslek Yüksekokulu, Gıda İşleme Bölümü
dc.description.abstractCirsium italicum (Savi) DC. was researched for its phytochemicals for the first time. Two new biflavonoids, 5,5'',7''-trihydroxy-3,7-dimethoxy-4'-4'''-O-biflavone (3), (8,3',4',5'-tetrahydroxy-7-O-alpha-glucosyl isoflavone)-6-8''-(4'''-hydroxy-7''-O-alpha-glucosyl isoflavone) biflavone (7), a new isoflavone, 6-2'-dihydroxy-5-methoxy isoflavonone-4'-O-alpha-D-glucopyranoside (5) and a new phenolic compound, ethyl-(2,3-dihydroxy-5,6-dimethoxy-4-acetyl) benzoate (4), together with three known compounds (1), (2) and (6) were isolated from Cirsium italicum. Their structures were elucidated by extensive 1D and 2D NMR, and MS data analyses. All compounds isolated from C. italicum exhibited antioxidant activity. However, the highest activity of the EtOAc extract is considered to be responsible for compounds (1), (2) and (3) being the main compounds. [GRAPHICS] .
dc.description.sponsorshipTUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [116Z450]
dc.description.sponsorshipWe would like to thank TUBITAK for financial support of the project (116Z450). The authors thanks to Prof. Dr. A. Orak for his assistance with the statistical evaluations.
dc.identifier.doi10.1080/14786419.2019.1630121
dc.identifier.endpage1619
dc.identifier.issn1478-6419
dc.identifier.issn1478-6427
dc.identifier.issue10en_US
dc.identifier.pmid31219371
dc.identifier.scopus2-s2.0-85067857936
dc.identifier.scopusqualityQ2
dc.identifier.startpage1613
dc.identifier.urihttps://doi.org/10.1080/14786419.2019.1630121
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5994
dc.identifier.volume35
dc.identifier.wosWOS:000473063900001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorŞabudak, Temine
dc.institutionauthorÇalışkan, Hilmican
dc.institutionauthorOrak, Hakime Hülya
dc.institutionauthorÖzer, Merve
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofNatural Product Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCirsium italicum
dc.subjectbiflavonoids
dc.subjectisoflavones
dc.subjectphenolic compounds
dc.subjectantioxidant activity
dc.subjectJaponicum Var. Maackii
dc.subjectAntioxidant Activity
dc.subjectGlycosides
dc.titleBiological activity of new flavonoids and phenolic compounds from Cirsium italicum (Savi) DC.
dc.typeArticle

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