Synthesis, Reactivity and Biological Properties of Methoxy-Activated Indoles

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dc.authorscopusid55308985300
dc.authorscopusid26029066300
dc.authorscopusid55326408200
dc.authorscopusid16833488100
dc.authorscopusid57226666676
dc.contributor.authorŞengül, İbrahim Fazıl
dc.contributor.authorBingül, Murat
dc.contributor.authorKandemir, Hakan
dc.contributor.authorKumar, Naresh
dc.contributor.authorBlack, David StC.
dc.date.accessioned2022-05-11T14:04:40Z
dc.date.available2022-05-11T14:04:40Z
dc.date.issued2021
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümü
dc.description.abstractIndoles continue to play a central role in the development of new structures of chemical and biological interest. They are the source of numerous biologically active natural products by virtue of their derivation from tryptophan units which are essential to peptide, protein and enzyme structures. Although the indole unit is electron rich and displays a wide range of reactivity, many naturally-occurring indoles contain methoxy substituents, which enhance their reactivity. The synthesis of methoxyindoles has also become a strategy for diversifying the regiochemical behaviour of indoles. This review brings together a wide range of information relating to indoles incorporating one, two, or three methoxy groups. It deals with aspects of synthesis, reactivity, and biological activity as well as summarizing the scope of important natural products © 2021, Targets in Heterocyclic Systems.All Rights Reserved.
dc.description.sponsorshipUniversity of New South Wales, UNSW
dc.description.sponsorshipWe thank the University of New South Wales and the Turkish Government for financial support.
dc.identifier.doi10.17374/targets.2022.25.162
dc.identifier.endpage212
dc.identifier.issn1724-9449
dc.identifier.scopus2-s2.0-85124719509
dc.identifier.scopusqualityQ4
dc.identifier.startpage162
dc.identifier.urihttps://doi.org/10.17374/targets.2022.25.162
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4704
dc.identifier.volume25
dc.identifier.wosWOS:000758279000008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorKandemir, Hakan
dc.language.isoen
dc.publisherSocieta Chimica Italiana
dc.relation.ispartofTargets in Heterocyclic Systems
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.titleSynthesis, Reactivity and Biological Properties of Methoxy-Activated Indoles
dc.typeArticle

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