Synthesis, Reactivity and Biological Properties of Methoxy-Activated Indoles

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Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Societa Chimica Italiana

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Indoles continue to play a central role in the development of new structures of chemical and biological interest. They are the source of numerous biologically active natural products by virtue of their derivation from tryptophan units which are essential to peptide, protein and enzyme structures. Although the indole unit is electron rich and displays a wide range of reactivity, many naturally-occurring indoles contain methoxy substituents, which enhance their reactivity. The synthesis of methoxyindoles has also become a strategy for diversifying the regiochemical behaviour of indoles. This review brings together a wide range of information relating to indoles incorporating one, two, or three methoxy groups. It deals with aspects of synthesis, reactivity, and biological activity as well as summarizing the scope of important natural products © 2021, Targets in Heterocyclic Systems.All Rights Reserved.

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Anahtar Kelimeler

Kaynak

Targets in Heterocyclic Systems

WoS Q Değeri

N/A

Scopus Q Değeri

Q4

Cilt

25

Sayı

Künye