Investigation of phage and molasses interactions for the biocontrol of E. coli O157:H7

dc.authorscopusid57205764029
dc.authorscopusid57196454965
dc.authorscopusid56403368300
dc.authorscopusid38461066500
dc.authorscopusid57403809800
dc.authorscopusid6603211547
dc.contributor.authorEvran, S.
dc.contributor.authorTayyarcan, E.K.
dc.contributor.authorAcar-Soykut, E.
dc.contributor.authorGüven, B.
dc.contributor.authorDuraklı Velioğlu, Serap
dc.contributor.authorBoyacı, İsmail Hakkı
dc.date.accessioned2022-05-11T14:07:10Z
dc.date.available2022-05-11T14:07:10Z
dc.date.issued2022
dc.departmentFakülteler, Ziraat Fakültesi, Gıda Mühendisliği Bölümü
dc.description.abstractResistance to antibiotics is one of the most critical health problems in the world. Therefore, finding new treatment methods to be used as alternatives to antibiotics has become a priority for researchers. Similar to phages, certain products containing antimicrobial components, such as molasses, are widely used to eliminate resistant bacteria. Molasses has a strong antimicrobial effect on bacterial cells, and this effect is thought to be due to the breakdown of the cytoplasmic cell membrane and cell proteins of the polyphenols in molasses. In the present study, phage–molasses interactions were investigated to examine the effects of concomitant use. It was found that molasses samples increased the size of phage plaques by up to 3-fold, and MIC and 1/2 x MIC concentrations of molasses increased the burst size of phages. Although no synergistic effect was found between the phage and molasses, the antimicrobial activities of the components and the effect of molasses on phage activity were demonstrated. © 2022, Canadian Science Publishing. All rights reserved.
dc.description.sponsorshipEmine Ku€bra Tayyarcan is supported by the 100/ 2000 doctoral scholarship provided by the Council of Higher Education, Turkey.
dc.identifier.doi10.1139/cjm-2021-0211
dc.identifier.endpage65
dc.identifier.issn0008-4166
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85122485691
dc.identifier.scopusqualityQ2
dc.identifier.startpage55
dc.identifier.urihttps://doi.org/10.1139/cjm-2021-0211
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4992
dc.identifier.volume68
dc.identifier.wosWOS:000740699600005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorDuraklı Velioğlu, Serap
dc.language.isoen
dc.publisherCanadian Science Publishing
dc.relation.ispartofCanadian Journal of Microbiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBacteriophage
dc.subjectEscherichia coli O157H7
dc.subjectMolasses
dc.subjectPhage therapy
dc.subjectSynergism
dc.subjectantibiotic resistance
dc.subjectbacteriophage
dc.subjectbiological control
dc.subjectcell
dc.subjectcoliform bacterium
dc.subjectconcentration (composition)
dc.subjectphenol
dc.subjectprotein
dc.subjectsynergism
dc.titleInvestigation of phage and molasses interactions for the biocontrol of E. coli O157:H7
dc.typeArticle

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