Investigation of phage and molasses interactions for the biocontrol of E. coli O157:H7
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Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Canadian Science Publishing
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Resistance to antibiotics is one of the most critical health problems in the world. Therefore, finding new treatment methods to be used as alternatives to antibiotics has become a priority for researchers. Similar to phages, certain products containing antimicrobial components, such as molasses, are widely used to eliminate resistant bacteria. Molasses has a strong antimicrobial effect on bacterial cells, and this effect is thought to be due to the breakdown of the cytoplasmic cell membrane and cell proteins of the polyphenols in molasses. In the present study, phage–molasses interactions were investigated to examine the effects of concomitant use. It was found that molasses samples increased the size of phage plaques by up to 3-fold, and MIC and 1/2 x MIC concentrations of molasses increased the burst size of phages. Although no synergistic effect was found between the phage and molasses, the antimicrobial activities of the components and the effect of molasses on phage activity were demonstrated. © 2022, Canadian Science Publishing. All rights reserved.
Açıklama
Anahtar Kelimeler
Bacteriophage, Escherichia coli O157H7, Molasses, Phage therapy, Synergism, antibiotic resistance, bacteriophage, biological control, cell, coliform bacterium, concentration (composition), phenol, protein, synergism
Kaynak
Canadian Journal of Microbiology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
68
Sayı
1
