Relationship between Empty Sella Syndrome and Hashimoto's Thyroiditis

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dc.authorid0000-0001-5584-4954
dc.authorid0000-0001-8084-848X
dc.authorid0000-0003-2050-4444
dc.authorscopusid55753696900
dc.authorscopusid36656843500
dc.authorscopusid36722143700
dc.authorscopusid35422880400
dc.authorscopusid36926020100
dc.authorscopusid35517398400
dc.authorwosidÖztürk, Feyza Yener/AAL-3013-2020
dc.authorwosidZuhur, Sayid/AAC-6839-2020
dc.authorwosidÖzel, Alper/AAL-3619-2020
dc.contributor.authorKuzu, İdris
dc.contributor.authorZuhur, Sayid Shafi
dc.contributor.authorÖzel, Alper
dc.contributor.authorOjalvo, David
dc.contributor.authorÖztürk, Feyza Yener
dc.contributor.authorAltuntaş, Yüksel
dc.date.accessioned2022-05-11T14:39:54Z
dc.date.available2022-05-11T14:39:54Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractPurpose: It is not clear if Hashimoto's thyroiditis leads to Empty sella syndrome. In the present study, we aimed to investigate if Hashimoto's thyroiditis was associated with Empty sella syndrome, and Hashimoto's thyroiditis was a secondary cause od some cases of primary Empty sella syndrome. Material and Method: Eighty-one patients who were diagnosed with primary Empty sella syndrome were included in the study. All patients underwent thyroid ultrasonography and biochemical tests for thyroid-stimulating hormone, free triiodothyronine, free thyroxine, anti thyroid peroxidase, anti thyroglobulin, follicle stimulating hormone, luteinizing hormone, 17 beta estradiol, growth hormone, insulin-like growth factor 1, adrenocorticotropic hormone and total testosterone for Hashimoto's thyroiditis and pituitary hormone deficiency. Results: Out of 81 patients, thyroid disease was diagnosed in 34 (42%) patients; 18 of them had Hashimoto's thyroiditis (22.2%) and 16 (19.8%) had central hypothyroidism. Among Hashimoto's thyroiditis patients, 11 (13.6%) had hypothyroidism and 7 (8.6%) were euthyroid. Discussion: In conclusion, it is possible that some cases of primary Empty sella syndrome are caused by Hashimoto's thyroiditis. It is recommended that the presence of Hashimoto's thyroiditis should be investigated in patients with primary Empty sella syndrome. Further studies investigating anti-pituitary antibody in patients with primary Empty sella syndrome, are needed to further declare this relationship.
dc.identifier.doi10.4274/tjem.3558
dc.identifier.endpage82
dc.identifier.issn1301-2193
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84990868190
dc.identifier.scopusqualityQ4
dc.identifier.startpage78
dc.identifier.urihttps://doi.org/10.4274/tjem.3558
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8791
dc.identifier.volume20
dc.identifier.wosWOS:000393327900003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorZuhur, Sayid Shafi
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofTurkish Journal of Endocrinology and Metabolism
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPrimary Empty sella syndrome
dc.subjectHashimoto's thyroiditis
dc.subjecthypopituitarism
dc.subjectLymphocytic Hypophysitis
dc.subjectAntipituitary Antibodies
dc.subjectPrimary Hypothyroidism
dc.subjectAutoimmune
dc.subjectDisease
dc.subjectTherapy
dc.subjectHypopituitarism
dc.subjectPrevalence
dc.subjectPatient
dc.subjectStates
dc.titleRelationship between Empty Sella Syndrome and Hashimoto's Thyroiditis
dc.title.alternativeEmpty sella sendromu ve hashimoto tiroiditi arasındaki ılişki]
dc.typeArticle

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