Relationship between Empty Sella Syndrome and Hashimoto's Thyroiditis
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Dosyalar
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Galenos Yayincilik
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose: It is not clear if Hashimoto's thyroiditis leads to Empty sella syndrome. In the present study, we aimed to investigate if Hashimoto's thyroiditis was associated with Empty sella syndrome, and Hashimoto's thyroiditis was a secondary cause od some cases of primary Empty sella syndrome. Material and Method: Eighty-one patients who were diagnosed with primary Empty sella syndrome were included in the study. All patients underwent thyroid ultrasonography and biochemical tests for thyroid-stimulating hormone, free triiodothyronine, free thyroxine, anti thyroid peroxidase, anti thyroglobulin, follicle stimulating hormone, luteinizing hormone, 17 beta estradiol, growth hormone, insulin-like growth factor 1, adrenocorticotropic hormone and total testosterone for Hashimoto's thyroiditis and pituitary hormone deficiency. Results: Out of 81 patients, thyroid disease was diagnosed in 34 (42%) patients; 18 of them had Hashimoto's thyroiditis (22.2%) and 16 (19.8%) had central hypothyroidism. Among Hashimoto's thyroiditis patients, 11 (13.6%) had hypothyroidism and 7 (8.6%) were euthyroid. Discussion: In conclusion, it is possible that some cases of primary Empty sella syndrome are caused by Hashimoto's thyroiditis. It is recommended that the presence of Hashimoto's thyroiditis should be investigated in patients with primary Empty sella syndrome. Further studies investigating anti-pituitary antibody in patients with primary Empty sella syndrome, are needed to further declare this relationship.
Açıklama
Anahtar Kelimeler
Primary Empty sella syndrome, Hashimoto's thyroiditis, hypopituitarism, Lymphocytic Hypophysitis, Antipituitary Antibodies, Primary Hypothyroidism, Autoimmune, Disease, Therapy, Hypopituitarism, Prevalence, Patient, States
Kaynak
Turkish Journal of Endocrinology and Metabolism
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
20
Sayı
3
