Dose dependent effects of Spirulina platensis on liver health in rats

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dc.authorscopusid55921065100
dc.authorscopusid56320836200
dc.authorscopusid6506008074
dc.contributor.authorSeyidoğlu, Nilay
dc.contributor.authorİnan, Sevda
dc.contributor.authorGüneş, Nazmiye
dc.date.accessioned2022-05-11T14:05:15Z
dc.date.available2022-05-11T14:05:15Z
dc.date.issued2020
dc.departmentFakülteler, Veteriner Fakültesi, Temel Bilimler Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractSpirulina platensis which is an important microalgae is interested in both human and animal nutrition for health balance. This study's aimed to evaluate the dose dependent effects of S.platensis on body weight, height, waist circumference (WC), body mass index (BMI), waist/height ratio (WHtR), abdominal fat weight, liver weight, serum liver enzymes and liver histopathology. 30 male Wistar albino rats're used in groups; Control, SP-1(500mg/kgbw) and SP-2(1000mg/kgbw). S.platensis was administered by oral gavage daily. The body weight, height, WC, BMI, WHtR and abdominal lipid weight were calculated. Also, serum cholesterol, ALT and AST were measured. End of the study, liver tissue samples were taken and scaled and histopathologic changes were recorded. There were no differences in body conditions, but positively significant correlations were found among parameters. As the doses were considered, in groupSP-1, significant positively correlations were determined among abdominal fat, growth, height, BMI and WC statistically. Nevertheless, there were no significant changes in liver weight, serum and histopathologic analyzes. S.platensis with its high concentration of functional nutrients is called as an important alternative therapeutic food and it can be used safely. © 2020 Agricultural Research Communication Centre. All rights reserved.
dc.description.sponsorship16.074, NKUBAP.10
dc.description.sponsorshipThis study was supported by grant from the Research Foundations of Namik Kemal University (Project number: NKUBAP.10.GA.16.074). The students acknowledge Eylül Yıldız, Chamza Taskir and thank for their technical assistance during research.
dc.identifier.doi10.18805/ijar.B-1055
dc.identifier.endpage353
dc.identifier.issn0367-6722
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85082817060
dc.identifier.scopusqualityQ2
dc.identifier.startpage349
dc.identifier.urihttps://doi.org/10.18805/ijar.B-1055
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4933
dc.identifier.volume54
dc.identifier.wosWOS:000522456700015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorSeyidoğlu, Nilay
dc.language.isoen
dc.publisherAgricultural Research Communication Centre
dc.relation.ispartofIndian Journal of Animal Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBody condition
dc.subjectCholesterol
dc.subjectLiver health
dc.subjectMicroalgae
dc.subjectSpirulina platensis
dc.subjectalanine aminotransferase
dc.subjectaspartate aminotransferase
dc.subjectcholesterol
dc.subjectSpirulina extract
dc.subjectabdominal fat
dc.subjectanimal experiment
dc.subjectArthrospira platensis
dc.subjectArticle
dc.subjectbody mass
dc.subjectbody weight
dc.subjectbody weight gain
dc.subjectcholesterol blood level
dc.subjectenzyme linked immunosorbent assay
dc.subjectfood intake
dc.subjectlipid blood level
dc.subjectliver
dc.subjectliver injury
dc.subjectliver tissue
dc.subjectliver weight
dc.subjectmale
dc.subjectnonhuman
dc.subjectrat
dc.subjectwaist circumference
dc.subjectwaist to height ratio
dc.titleDose dependent effects of Spirulina platensis on liver health in rats
dc.typeArticle

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