Dose dependent effects of Spirulina platensis on liver health in rats
Yükleniyor...
Dosyalar
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Agricultural Research Communication Centre
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Spirulina platensis which is an important microalgae is interested in both human and animal nutrition for health balance. This study's aimed to evaluate the dose dependent effects of S.platensis on body weight, height, waist circumference (WC), body mass index (BMI), waist/height ratio (WHtR), abdominal fat weight, liver weight, serum liver enzymes and liver histopathology. 30 male Wistar albino rats're used in groups; Control, SP-1(500mg/kgbw) and SP-2(1000mg/kgbw). S.platensis was administered by oral gavage daily. The body weight, height, WC, BMI, WHtR and abdominal lipid weight were calculated. Also, serum cholesterol, ALT and AST were measured. End of the study, liver tissue samples were taken and scaled and histopathologic changes were recorded. There were no differences in body conditions, but positively significant correlations were found among parameters. As the doses were considered, in groupSP-1, significant positively correlations were determined among abdominal fat, growth, height, BMI and WC statistically. Nevertheless, there were no significant changes in liver weight, serum and histopathologic analyzes. S.platensis with its high concentration of functional nutrients is called as an important alternative therapeutic food and it can be used safely. © 2020 Agricultural Research Communication Centre. All rights reserved.
Açıklama
Anahtar Kelimeler
Body condition, Cholesterol, Liver health, Microalgae, Spirulina platensis, alanine aminotransferase, aspartate aminotransferase, cholesterol, Spirulina extract, abdominal fat, animal experiment, Arthrospira platensis, Article, body mass, body weight, body weight gain, cholesterol blood level, enzyme linked immunosorbent assay, food intake, lipid blood level, liver, liver injury, liver tissue, liver weight, male, nonhuman, rat, waist circumference, waist to height ratio
Kaynak
Indian Journal of Animal Research
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
54
Sayı
3
