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Yazar "Akkoyun, Dursun Çayan" seçeneğine göre listele

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    A new approach to the measurement of heart rate in patients with chronic heart failure-Heart rate performance index: an observational study
    (Aves, 2013) Akyüz, Aydın; Alpsoy, Şeref; Akkoyun, Dursun Çayan; Güler, Niyazi
    Objective: In order to evaluate the utility of the heart rate performance index (HRPI), which is obtained by dividing HR mean by the difference of HR max and HR min in the context of Holter monitoring, we sought to determine whether there was any correlation or relationship between the HRPI and LVEF values as determined by echocardiography and to compare the HRPI between the study and control groups. Methods: This study is a cross-sectional, controlled observational study. Thirty-two patients with symptomatic or asymptomatic left ventricular systolic dysfunction (LVEF <45%) were included as study group and 32 subjects without chronic heart failure (CHF) were included as a control group. In the study group, 10 patients were in NYHA class I (31.2%), 12 - were in NYHA class II (37.6%) and 10 - were in NYHA class III (31.2%). Heart rate analysis was measured using 24-hour Holter ambulatory electrocardiography. To determine the HRPI, the difference between maximum (HR max) and minimum heart rate (HR min) was divided by mean heart rate (HR mean) (beats/minute): HRPI=(HR max-HR min) / HR mean. Statistical analysis was performed using t-test for independent samples, Mann-Whitney U test, Chi-square test, Kruskal-Wallis test, Pearson's correlation and linear regression analyses. Results: The HRPI index value was markedly decreased [0.83 (0.58-1.1) and 1.10 (0.74-1.3), p<0.001] in the study group as compared to the control group. The data collected for the study group and the control group (n=64) demonstrated a positive correlation between the HRPI and LVEF (r=0.62, p<0.001) as well as a negative correlation between the HR mean and LVEF (r=-0.39, p<0.003). The HR mean was higher (80.2 +/- 11.3 and 75.2 +/- 6.7, p<0.007) and HR max-HR min (67.9 +/- 11.6 and 83.3 +/- 14.3, p<0.001) were lower in the study group as compared to the control group. Linear regression analysis demonstrated no significant relationship between LVEF and HRPI and other heart rate derivatives (unstandardized beta=42.43 95% CI: 21.98-50.51, p=0.231). Conclusion: According to our findings, patients with CHF exhibited higher HR mean values, reduced HR max-min values and significantly decreased HRPI values. There is a positive correlation between HRPI and LVEF, a decreased HRPI is associated with a decreased LVEF, but there is no relationship between these two variables. Therefore HRPI values may represent a viable option for assessing daily exercise activity and potentially sympathetic activation in patients with CHF. The assessment of HRPI may be helpful the evaluation of CHF patients, as well as resting HR.
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    Akciğer Ve Sağ Kalp Tutulumu Olan Bir Kist Hidatik Olgusu
    (Namık Kemal Üniversitesi, Tıp Fakültesi, 2013) Akyüz, Aydın; Es, Mehmet Uğur; Alpsoy, Şeref; Akkoyun, Dursun Çayan
    Echinococcus granulosus ile oluşan kist hidatik hastalığı endemiktir ve halen ciddi bir hastalıktır. Kardiyak ekinokokoz is çok nadir görülür. Bu yazıda kuru öksürük, egzersize bağlı nefes darlığı ve halsizlik şikâyeti ile birlikte gelen ve hem kalp hem de akciğer tutulumu olan bir olgumuzu bildirmeyi amaçladık
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    An imaging of paradox flow in coronary artery collateralization
    (2013) Akyüz, Aydın; Alpsoy, Şeref; Akkoyun, Dursun Çayan; Güler, Niyazi
    [No abstract available]
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    Anomalous origin of left internal mammary artery from distal subclavian artery
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2014) Uygur, Ramazan; Akyüz, Aydın; Çağlar, Veli; Alpsoy, Şeref; Akkoyun, Dursun Çayan
    The internal mammary artery arises from the first part of the subclavian artery. The left internal mammary artery (LIMA) is an excellent graft for myocardial revascularization of the left anterior descending artery. In this article, we describe a quite important variation of an anomalous origin of LIMA, which is rarely seen. In our case, LIMA was arising from the distal of the third part of the subclavian artery. Therefore, it is of utmost importance to perform LIMA angiography before coronary artery bypass grafting surgery.
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    Anomaly of the Conus Artery Arising from the Right Coronary Artery
    (Taiwan Soc Cardiology, 2013) Çağlar, Veli; Akyüz, Aydın; Uygur, Ramazan; Alpsoy, Şeref; Akkoyun, Dursun Çayan
    Some anomalies of the conus artery are relatively common, such as those arising from the discrete ostium of the right coronary artery. We report a 63 y/o male with an unusual anatomic variation of the conus artery terminating in the pericardium. Coronary anomalies may cause coronary ischemia, infarction and sudden cardiac death; hence, it is significant to identify coronary anomalies. Here, we identify an unusual conus artery anomaly for the first time, with accompanying imaging showing its very rare anatomical features that may be of interest to the larger medical community.
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    Association between blood group antigens and rheumatic valve involvement and severity in endemic areas
    (Elsevier Science Bv, 2013) Ercan, Süleyman; Altunbaş, Gökhan; Akkoyun, Dursun Çayan; Davutoglu, Vedat; Deniz, Hayati
    Background: Rheumatic valve disease is an important public health problem in developing countries. We sought to evaluate the possible role of blood antigens as a risk factor for severe rheumatic valve disease. Methods: Two hundred and fifty-four patients with severe rheumatic mitral and/or aortic valve disease with the surgical indication were enrolled to the study. Control group was composed of age and gender matched 2668 healthy volunteers. Results: There were 216 patients with aortic valve involvement and 249 patients with mitral valve involvement. One hundred and seventy-five patients had mitral stenosis, 96 patients had severe mitral regurgitation and 61 patients had severe aortic regurgitation. The distribution of blood groups among patients was as follows: Group A-42.9%, Group B=19.2%, Croup AB =8.6%, and Croup O=29.1%. The distribution of blood groups in the control group was Group A=40.8%, Group B =16.4%, Croup AB=7.6%, and Croup O=35.1%. There was no significant difference between blood groups of patients and controls (p=0.141). Conclusion: Blood group does not seem to be a risk factor for rheumatic valve involvement or severity of the disease. (C) 2013 The Czech Society of Cardiology. Published by Elsevier Urban & Partner Sp.z.o.o. All rights reserved.
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    Association between blood group antigens and rheumatic valve involvement and severity in endemic areas (Meeting Abstract)
    (Elsevier Science Inc, 2013) Ercan, Süleyman; Altunbaş, Gökhan; Akkoyun, Dursun Çayan; Davutoglu, Vedat; Deniz, Hayati
    [No Abstract Available]
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    Association Between Serum Fetuin-A levels, Carotid Artery Stiffness, and Intima-Media Thickness in Patients With Normotensive Obstructive Sleep Apnea Syndrome
    (Sage Publications Inc, 2014) Akyüz, Aydın; Oran, Mustafa; Alpsoy, Şeref; Mutlu, Levent Cem; Akkoyun, Dursun Çayan; Güzel, Savaş; Alp, Recep
    Increased carotid intima-media thickness (cIMT) and stiffness, reflecting subclinical atherosclerosis, are associated with obstructive sleep apnea syndrome (OSAS). The relationship between serum fetuin-A, which inhibits ectopic calcification, and atherosclerosis is unclear. Therefore, we investigated the association between serum fetuin-A levels and carotid artery stiffness and cIMT in patients with normotensive OSAS (n = 50) and non-OSAS controls (n = 38). Compared with controls, there were lower fetuin-A levels (59.4 +/- 6.5 vs 68.2 +/- 5.8 ng/mL, P = .029), higher mean cIMT (0.73 +/- 0.2 vs 0.63 +/- 0.3 mm, P < .001), and greater stiffness (beta) index (7.45 +/- 0.9 vs 5.2 +/- 0.7, P = .001) in the OSAS group. The cIMT and stiffness (beta) index were inversely correlated with fetuin-A levels (r = -.324, P = .033; r = -.466, P < .001, respectively) and positively correlated with apnea hypopnea index (r = .498, P < .001; r = .422, P = .001, respectively) in the OSAS group. Decreased serum fetuin-A levels were associated with subclinical carotid atherosclerosis in patients with normotensive OSAS.
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    Association of coronary artery disease severity and disulphide/native thiol ratio
    (Modestum Ltd, 2017) Bilir, Bülent; Akkoyun, Dursun Çayan; Aydın, Murat; Özkaramanlı Gür, Demet; Değirmenci, Hasan; Albayrak, Neslihan; Erel, Özcan
    Objective: Oxidative stress is among the major components of cardiovascular disease pathogenesis. Thiols play a significant role in prevention of oxidative stress in the cell. The purpose of this study is to investigate the relationship between the severity of coronary artery disease and disulphide/native thiol ratio, also determine if this ratio can be used as a marker of oxidative stress in this population. Methods: A total number of 107 patients with angiographically established coronary artery disease and 26 control subjects with normal coronary arteries were enrolled. The mean Gensini score of patients were calculated (mean=30) and a score of 29 or below was considered as mild and a score of 30 or higher coronary artery disease as severe. Serum total, native thiol was measured and the disulphide and disulphide/native thiol ratio were calculated as described by Erel&Neselioglu. Results: Patients with mild and severe coronary artery disease had significantly lower native thiol levels and higher disulphide/native thiol ratio levels when compared to the control subjects. Also severe disease's disulphide/native thiol ratio were higher than mild. Conclusion: The increased disulphide/ native thiol ratio related with the severity of coronary artery disease, may reflect the augmented oxidative stress in coronary artery disease.
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    Association of coronary artery disease severity and disulphide/native thiol ratio (vol 14, pg 30, 2017)
    (Modestum Ltd, 2018) Bilir, Bülent; Akkoyun, Dursun Çayan; Aydın, Murat; Özkaramanlı Gür, Demet; Kara, Sonat Pınar; Değirmenci, Hasan; Erel, Özcan
    [No Abstract Available]
  • Küçük Resim Yok
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    Atherosclerosis, some serum inflammatory markers in psoriasis
    (Edizioni Minerva Medica, 2014) Alpsoy, Şeref; Akyuz, A.; Erfan, Gamze; Akkoyun, Dursun Çayan; Topçu, Birol; Güzel, Savaş; Kulaç, Mustafa
    Aim. Psoriasis is an autoimmune inflammatory disease which is associated with increased inflammatory markers and atherosclerosis. We wanted to investigate whether there is a relationship between some inflammatory markers and subclinical atherosclerosis markers. Methods. We studied 60 psoriasis patients and 50 healthy controls. Demographic, biochemical parameters, C3, C4, d-dimer, CRP, fibrinogen and YKL-40 (human cartilage glyco-protein-39) levels were measured. After measuring carotid intima-media thickness (cIMT) and aortic elasticity parameters such as aortic strain, (beta) stiffness index and compliance, statistical comparisons were done. Results. Patients with psoriasis had significantly higher diastolic blood pressure, CRP, fibrinogen, C3, uric acid levels, beta-stiffness index, and cIMT values than the control group. cIMT was correlated with CRP, YKL-40 and psoriasis area and severity index (PASI) score (r=0.219, P=0.038; r=0.225, P=0.033 and r=0.275, P=0.034). Aortic strain (%), aortic compliance and aortic stiffness index were correlated with C3 (r=-0.349, r=-0.526 and r=0.235) and fibrinogen (r=-0.354, r=-0.275 and r=0.289), all P values <0.05, but not with PASI score. The presence of psoriasis was related to aortic strain (beta +/- SE: -2.055 +/- 0.861, P=0.019) and beta-stiffness index (beta +/- SE: 2.934 +/- 1.143, P=0.012). Conclusion. Serum C3, CRP, fibrinogen and YKL-40 levels are elevated as well as increased cIMT and impaired aortic elasticity in psoriasis. CRP, YKL-40 and PASI score are correlated with cIMT. Increased serum C3 and fibrinogen levels correlate negatively with aortic strain and aortic compliance, and correlate positively with the beta-stiffness index.
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    Atrial Fibrillation Is Associated With Increased Mean Platelet Volume and Apnea Hypopnea Index in Patients With Obstructive Sleep Apnea
    (Sage Publications Inc, 2015) Akyüz, Aydın; Akkoyun, Dursun Çayan; Değirmenci, Hasan; Alp, Recep
    This study investigated whether there is a relationship between atrial fibrillation (AF), mean platelet volume (MPV), and apnea hypopnea index (AHI) in patients who have obstructive sleep apnea syndrome (OSAS). We enrolled patients who had OSAS with either AF or normal sinus rhythm (NSR). We divided 90 patients (aged 50-80 years) into 2 groups: group 1 consisted of 40 patients with OSAS having AF and group 2 of 50 patients with OSAS having NSR. Mean platelet volume was higher in patients with AF than in those with NSR (9.8 +/- 0.6 vs 8.4 +/- 0.6 fL; P < .001). The MPV and AHI were substantial variables associated with AF (odds ratio [OR] = 2.41; 95% confidence interval [CI], 1.36-5.26; P < .004 and OR = 1.91; 95% CI, 1.26-3.32; P = .02). Elevated MPV value of 9.4 fL is associated with AF (70% sensitivity and 63% specificity). More research is needed to establish the clinical relevance of this association.
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    Atriyal Fibrilasyon ile Başvuran Aort Koarktasyonu: Olgu Sunumu
    (Namık Kemal Üniversitesi, Tıp Fakültesi, 2013) Alpsoy, Şeref; Akyüz, Aydın; Akkoyun, Dursun Çayan; Gürkan, Selami; Değirmenci, Hasan
    Aort koarktasyonu dikkatli fizik muayene ile bebeklik ve çocukluk çağında kolay tanı konabilen doğumsal kalp hastalıklarından biridir. Erken tanı konulamayan ve erişkin yaşa ulaşan hastalar genellikle hipertansiyon ile başvururlar. Komplikasyonlar geliştiği zaman genellikle ölümle sonuçlandığı için aort koarktasyonu teşhis edilir edilmez uygun vakalarda stent implantasyonu veya cerrahi onarım hayati önem taşımaktadır. Atrial fibrilasyon, biküspit aort kapak, çıkan aorta anevrizması ve aort koarktasyonu olan bir hastayı sunduk.
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    Author's reply
    (Turkish Society of Cardiology, 2016) Akkoyun, Dursun Çayan; Akyüz, Aydın; Kurt, Ömer; Bilir, Bülent; Alpsoy, Şeref; Güler, Niyazi
    [No abstract available]
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    Çocuklarda kilo fazlalığının kalp fonksiyonlarına etkisi
    (2013) Alpsoy, Şeref; Akyüz, Aydın; Akkoyun, Dursun Çayan; Nalbantoğlu, Burçin; Topçu, Birol; Değirmenci, Hasan; Donma, Mustafa Metin
    Amaç: Obezitenin kalp yetersizliği riski ile ilişkili olduğu bilinmektedir. Semptomsuz sol ventrikül (SV) diyastolik fonksiyon bozukluğu kalp yetersizliği gelişmesi ile ilişkilidir. Çocuklarda kilo fazlalığının subklinik SV diyastolik fonksiyon bozukluğu ile ilişkili olup olmadığı belli değildir. Bu çalışmanın amacı kilolu çocuklarda SV kitle indeksi ve SV diyastolik fonksiyonları üzerine beden kütle indeksi (BKİ) ve bel çevresinin etkisini değerlendirmektir. Çalışma planı: Çalışmaya normal kilolu (yaşa göre ayarlanmış BKİ: %15-85 arası) 91 ve fazla kilolu (yaşa göre ayarlanmış BKİ: %85-95 arası) 61 olmak üzere toplam 153 çocuk katıldı. İki boyutlu, M-Mode görüntüleme ile boyutlar ve çaplar ölçüldü. SV diyastolik fonksiyonu geleneksel ve doku Doppler görüntüleme ile değerlendirildi. Bulgular: Kilolu çocuklarda yüksek yoğunluklu kolesterol düşük, sistolik ve diyastolik kan basıncı (KB), serum insülini, HOMA indeksi, trigliserit (TG), sol atriyum, aort ve SV çapları, SV duvar kalınlıkları, sol ventrikül kitlesi (SVK) ve sol ventrikül kitle indeksi (SVKİ) fazla idi. Mitral anülüs septal e, septal e/a, lateral e, lateral e/a, triküspit lateral anülüs e ve e/a değerleri düşüktü. Mitral anülüs septal e, lateral e, triküspit lateral anülüs e, mitral anülüs septal e/a, lateral e/a ve triküspit lateral anülüs e/a ile BKİ, bel çevresi, serum insülin düzeyi, HOMA indeksi, sistolik ve diyastolik KB arasında negatif korelasyon bulundu. SVKİ ile BKİ ve bel çevresi arasında pozitif korelasyon bulundu. Mitral anülüs septal e, septal e/a, lateral e, lateral e/a için sadece BKİ öngördürücü olarak tespit edildi. Sonuç: Normal kilolu çoçuklara kıyasla kilolu çocuklarda SV diyastolik fonksiyonlarında azalma vardır. Kilolu çocuklarda BKİ, SV diyastolik fonksiyonlarında azalma ile ilişkilidir.
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    Çocuklarda Obezitenin Sol Ventrikül Diyastolik Fonksiyonları Üzerine Etkisi
    (2013) Alpsoy, Şeref; Akyüz, Aydın; Akkoyun, Dursun Çayan; Nalbantoğlu, Burçin; Topçu, Birol; Değirmenci, Hasan; Donma, Mustafa Metin
    Amaç: Bu çalışmada obez ve normal kilolu çocuklarda iki boyutlu, M-Mod, geleneksel ve doku Doppler ekokardiyografi yle sol ventrikül diyastolik fonksiyon parametrelerini ölçmeyi ve bu parametreler üzerine antropometrik ve biyokimyasal faktörlerin etkilerini değerlendirmeyi amaçladık.Hastalar ve Yöntem: Bu olgu-kontrollü kesitsel çalışmaya, 8-15 yaş arası 60 obez ve 60 normal kilolu çocuk dahil edildi. Çocukların antropometrik ve biyokimyasal değerleriyle sol ventrikül ekokardiyografi k parametreleri ölçüldü ve aralarındaki ilişki araştırıldı.Bulgular: Obez grupta bel çevresi ve beden kitle indeksi (BKİ-Z) skoru, sistolik ve diyastolik kan basıncı, trigliserid, açlık kan şekeri, insülin ve homeostatik modeli değerlendirmesi (HOMD) indeksi anlamlı olarak yüksekken yüksek yoğunluklu lipoprotein kolesterol (YYL-K) konsantrasyonu anlamlı derecede düşük bulundu. Mitral annulus septal E' ve E'/A', mitral annulus lateral E' ve E'/A', anteriyor E' ve E'/A', inferiyor E' ve E'/A' değerleri anlamlı derecede düşük bulundu, mitral E'/septal E' ve mitral E/lateral E değerleri anlamlı olarak daha yüksekti. Çoğu doku Doppler parametreleri ile bel çevresi, BKİ-Z skoru, açlık kan şekeri, HOMD, serum insülin düzeyi sistolik ve diyastolik kan basıncı, trigliserid ve YYL-K arasında korelasyon vardı. Bel çevresi ve BKİ-Z skoru bazı doku Doppler parametreleri için belirleyiciydi.Sonuç: Obez çocuklarda akranlarına göre sol ventrikül diyastolik fonksiyonları bozulmuştur. Risk faktörleriyle diyastolik fonksiyon parametreleri arasında korelasyon olsa da, obezitenin kendisi sol ventrikül diyastolik fonksiyonlarında azalmayla ilişkilidir.
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    Cytotoxin associated gene A+ helicobacter pylori ınfection is related with endothelial dysfunction in normotensive ındividuals
    (2014) Akyüz, Aydın; Mete, Rafet; Oran, Mustafa; Alpsoy, Şeref; Akkoyun, Dursun Çayan; Değirmenci Osanmaz, Pelin; Avcı, Okan
    Giriş: Sitotoksin ilişkili A genli Helicobacter pylori (SİAGHP), en çok virülansı olan H. pylori tipidir ve halen endotelyal disfonksiyon ile ilişkisi belirsizdir. Bu nedenle biz SİAGHP’nin endotelyal bağımlı dilatasyon üzerine etkilerini ve C-reaktif protein (CRP) düzeyleri ile ilişkisini normotansif bireylerde araştırdık. Hastalar ve Yöntem: SİAGHP enfeksiyonu olan 60 kişi, sitotoksin ilişkili A geni negatif H. pylori (SAİGNHP) enfeksiyonlu 40 kişi ve enfeksiyonu olmayan 50 kişi ile akım aracılı dilatasyon (AAD), endotele bağımlı olmayan dilatasyon (EBOD) ve CRP düzeyleri yönünden karşılaştırıldı. Bulgular: SİAGHP’li bireylerde ortalama AAD’nin yüzdesi (6,3±2,7) SİAGNHP olanlardan (9,8±3,3, p<0,01) ve enfekte olmayan kontrol grubundan (10,1±2,6, p<0,01) belirgin olarak düşüktü. CRP’nin ortalama düzeyleri SİAGHP’li bireylerde 3,9 mg/dL (0,1-9,8 aralığında), SİAGNHP olanlardan (2,3 mg/dL, 0,1-5,4 aralığında, p=0,01) ve enfekte olmayan kontrol grubundan (1,9 mg/dL, 0,1-5,3 aralığında, p<0,01) daha yüksek idi. SİAGHP’li bireylerde CRP düzeyleri AAD ile ters korelasyon gösterdi (r=0,318, p=0,013), fakat EBOD ile bu korelasyon görülmedi. Sonuç: Azalmış AAD ve düşük düzeyde inflamasyon SİAGHP enfeksiyonu ile ilişkilidir, ancak SİAGNHP ile ilişkili değildir.
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    Demographics of patients with heart failure who were over 80 years old and were admitted to the cardiology clinics in Turkey
    (Turkish Soc Cardiology, 2019) Gök, Gülay; Zoghi, Mehdi; Sinan, Umit Yasar; Kılıç, Salih; Tokgozoglu, Lale; Sumerkan, Mutlu Cagan; Ari, Hatem; Akkoyun, Dursun Çayan; Alpsoy, Şeref
    Objective: Heart failure (HF) has a high prevalence and mortality rate in elderly patients; however, there are few studies that have focused on patients older than 80 years. The aim of this study is to describe and compare the age-specific demographics and clinical features of Turkish elderly patients with HF who were admitted to cardiology clinics. Methods: The Epidemiology of Cardiovascular Disease in Elderly Turkish population (ELDER-TURK) study was conducted in 73 centers in Turkey, and it recruited a total of 5694 patients aged 65 years or older. In this study, the clinical profile of the patients who were aged 80 years or older and those between 65 and 79 years with HF were described and compared based on the ejection fraction (EF)-related classification: HFrEF and HFpEF (is considered as EF: >= 50%). Results: A total of 1098 patients (male, 47.5%; mean age, 83.5 +/- 3.1 years) aged 80 years and 4596 patients (male, 50.2 %; mean age, 71.1 +/- 4.31 years) aged 65-79 years were enrolled in this study. The prevalence of HF was 39.8% for patients who were >= 80 years and 27.1% for patients 65-79 years old. For patients aged >= 80 years with HF, the prevalence rate was 67% for hypertension (HT), 25.6% for diabetes mellitus (DM), 54.3% for coronary artery disease (CAD), and 42.3% for atrial fibrilation. Female proportion was lower in the HFrEF group (p=0.019). The prevalence of HT and DM was higher in the HFpEF group (p<0.01), whereas CAD had a higher prevalence in the HFrEF group (p=0.02). Among patients aged 65-79 years, 43.9% (548) had HFpEF, and 56.1% (700) had HFrEF. In this group of patients aged 65-79 years with HFrEF, the prevalence of DM was significantly higher than in patients aged >= 80 years with HFrEF (p<0.01). Conclusion: HF is common in elderly Turkish population, and its frequency increases significantly with age. Females, diabetics, and hypertensives are more likely to have HFpEF, whereas CAD patients are more likely to have HFrEF.
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    Distal Sol Ön İnen Koroner Arter Anevrizmasının Neden Olduğu Egzersiz Uyumlu Miyokart İskemisi
    (2015) Alpsoy, Şeref; Akyüz, Aydın; Akkoyun, Dursun Çayan; Şahin, Ertan
    Koroner arterin anormal genişlemesini ifade eden koroner arter ektazi veya anevrizması anjiyografi yapılan hastalarda %3-8 oranında görülür. Asemptomatik olabildiği gibi, efor anjinası, kararsız anjina ve miyokart infarktüsüne yol açabilir. Sol ön inen koroner arter distalinde anevrizması ve stabil göğüs ağrısı olan bir olguyu sunmayı amaçladık.
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    Does Low Birth Weight Affect P-Wave and QT Dispersion in Childhood?
    (Wiley, 2013) Akyüz, Aydın; Alpsoy, Şeref; Akkoyun, Dursun Çayan; Nalbanto?lu, Burçin; Özdilek, Burcu; Donma, Mustafa Metin
    BackgroundThe aim of our study is to investigate the effects of low birth weight (LBW) on atrial conduction and ventricular repolarization in children by using P-wave dispersion (Pw-d) and QT dispersion (QT-d) analyses. These effects have not yet been studied in detail in LBW children. MethodsFifty LBW children and 70 normal birth weight (NBW) children were enrolled in this cross-sectional controlled study. The Pw-d and QT-d of the LBW and NBW children were investigated. Independent Student's t-test, Mann-Whitney U test, and (2) test were performed to compare these two groups. Stepwise multiple regression analysis was performed to investigate whether there was a relationship between P-wave indices, QT derivatives, anthropometric and clinical features, and echocardiographic parameters. ResultsAge, gender, body mass index, waist circumferences, systolic and diastolic blood pressure, and echocardiographic measurements were similar between the LBW group and the NBW group (all P values > 0.05). The following findings were recorded for the LBW and NBW groups, respectively: the Pw-d (30 [10-50] ms vs 30 [10-50] ms, P = 0.977), QT-d (20 [10-50] ms vs 30 [15-50] ms, P = 0.561), and QTc-d (26 [14-54] ms vs 33 [17-62] ms, P = 0.866). No significant difference was found in Pw-d, QT-d, and QTc-d in comparison between the groups (all P values > 0.05). Pw-d was related to left atrial diameter and QTc-d was associated with left ventricle mass index even though they were within the normal range. ConclusionCompared with the NBW group, no significant difference was found in both atrial conduction and ventricular repolarization features in LBW children.
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