Association between blood group antigens and rheumatic valve involvement and severity in endemic areas
Yükleniyor...
Dosyalar
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Bv
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Rheumatic valve disease is an important public health problem in developing countries. We sought to evaluate the possible role of blood antigens as a risk factor for severe rheumatic valve disease. Methods: Two hundred and fifty-four patients with severe rheumatic mitral and/or aortic valve disease with the surgical indication were enrolled to the study. Control group was composed of age and gender matched 2668 healthy volunteers. Results: There were 216 patients with aortic valve involvement and 249 patients with mitral valve involvement. One hundred and seventy-five patients had mitral stenosis, 96 patients had severe mitral regurgitation and 61 patients had severe aortic regurgitation. The distribution of blood groups among patients was as follows: Group A-42.9%, Group B=19.2%, Croup AB =8.6%, and Croup O=29.1%. The distribution of blood groups in the control group was Group A=40.8%, Group B =16.4%, Croup AB=7.6%, and Croup O=35.1%. There was no significant difference between blood groups of patients and controls (p=0.141). Conclusion: Blood group does not seem to be a risk factor for rheumatic valve involvement or severity of the disease. (C) 2013 The Czech Society of Cardiology. Published by Elsevier Urban & Partner Sp.z.o.o. All rights reserved.
Açıklama
Anahtar Kelimeler
Rheumatic valve disease, Blood group antigen
Kaynak
Cor Et Vasa
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
55
Sayı
5
