Evaluation of red cell distribution width (RDW) in diabetic nephropathy patients

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dc.authorscopusid57200105522
dc.authorscopusid57200105523
dc.authorscopusid55556342300
dc.authorscopusid14520105500
dc.authorscopusid55858591400
dc.authorscopusid7102765266
dc.contributor.authorBilir, Bülent
dc.contributor.authorEkiz Bilir, Betül
dc.contributor.authorSoysal Atile, N.
dc.contributor.authorTakır, M.
dc.contributor.authorYılmaz, A.
dc.contributor.authorAydın, M.
dc.date.accessioned2022-05-11T14:14:03Z
dc.date.available2022-05-11T14:14:03Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractDiabetic nephropathy (DN) is an important cause of morbidity and mortality of diabetes mellitus (DM) patients. Inflammation has a pivotal role in DN pathogenesis. Red cell distribution width (RDW) is a current parameter which has been supposed to be a marker of ineffective erythropoiesis depending on chronic inflammation and neurohumoral activation. We aimed to compare levels RDW which is a marker of inflammation between DM patients with and without diabetic nephropathy and also evaluate the effect of diabetic nephropathy on RDW in a total of 101 type 2 DM patients (58 diabetic nephropathy patients and 43 patients without diabetic nephropathy). All clinical and laboratory data including BUN, creatinine, hemogram, fasting blood glucose, HbA1c, lipid profile, and blood pressure levels were recorded. SPSS 17.0 was used for the statistical analysis of data. RDW values of diabetic nephropathy patients was significantly higher than those of patients without diabetic nephropathy (p=0.032). Fasting blood glucose, HbA1c, LDL-cholesterol levels and duration of diabetes were statistically significantly different (respectively p=0.01, 0.01, 0.048, <0.001), whereas triglycerides, HDL-cholesterol, creatinine levels, height and weight of the patients were not statistically significantly different (respec-tively p=0.939, 0.347, 0.128, 0.418, 0.851) between groups. Since RDW index is a cheap and easy method its use can be recommended in the evaluation of inflammation and atherosclerotic process in diabetic nephropathy patients. © 2016, Logos Medical Publishing. All rights reserved.
dc.identifier.doi10.5222/MMJ.2016.156
dc.identifier.endpage160
dc.identifier.issn2149-2042
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85044156738
dc.identifier.scopusqualityQ4
dc.identifier.startpage156
dc.identifier.urihttps://doi.org/10.5222/MMJ.2016.156
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5764
dc.identifier.volume31
dc.indekslendigikaynakScopus
dc.institutionauthorBilir, Bülent
dc.institutionauthorYılmaz, A.
dc.institutionauthorAydın, M.
dc.language.isotr
dc.publisherLogos Medical Publishing
dc.relation.ispartofMedeniyet Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDiabetes mellitus
dc.subjectDiabetic nephropathy
dc.subjectRDW
dc.titleEvaluation of red cell distribution width (RDW) in diabetic nephropathy patients
dc.title.alternativeDiyabetik nefropati hastalarında eritrosit dağılım aralığının (RDW) değerlendirilmesi]
dc.typeArticle

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