The expressions of some metabolic hormones (leptin, ghrelin and obestatin) in the tissues of sheep tongue

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dc.authorscopusid56521500300
dc.authorscopusid36650778800
dc.authorscopusid9842574500
dc.authorwosidErdogan, Serkan/F-5923-2011
dc.contributor.authorSağsöz, Hakan
dc.contributor.authorErdoğan, Serkan
dc.contributor.authorGüney Saruhan, Berna
dc.date.accessioned2022-05-11T14:42:26Z
dc.date.available2022-05-11T14:42:26Z
dc.date.issued2020
dc.departmentFakülteler, Veteriner Fakültesi, Temel Bilimler Bölümü, Anatomi Ana Bilim Dalı
dc.description.abstractIn this study, we aimed to observe the localization and expression of peptide hormones-leptin, ghrelin and obestatin-in the sheep tongue by immunohistochemistry. For that purpose, tongues of ten adult sheep were used. Leptin expression of moderate intensity was observed in the basal and parabasal epithelial cells of the luminal epithelium, and leptin was strongly expressed in the taste buds of the circumvallate and fungiform papillae and in von Ebner's glands. Ghrelin was primarily expressed in some of the skeletal muscle cells and the smooth muscle cells of the middle layer of blood vessels. A strong expression was observed in the epithelial cells lining the base of the groove surrounding the circumvallate papillae. Obestatin expression was particularly strong in the epithelial cells of the salivary ducts. It was also stronger in the von Ebner's glands than in the seromucous glands. Leptin, ghrelin and obestatin were shown to be produced at varying levels in different cell types, including epithelial, stromal and skeletal muscle cells, as well as in ganglion neurons, neural plexuses and blood vessels in the sheep tongue. Cellular localization and expression of these peptide hormones have not been investigated in many species including sheep.
dc.identifier.doi10.1111/ahe.12499
dc.identifier.endpage120
dc.identifier.issn0340-2096
dc.identifier.issn1439-0264
dc.identifier.issue1en_US
dc.identifier.pmid31568599
dc.identifier.scopus2-s2.0-85073995343
dc.identifier.scopusqualityQ2
dc.identifier.startpage112
dc.identifier.urihttps://doi.org/10.1111/ahe.12499
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9371
dc.identifier.volume49
dc.identifier.wosWOS:000488192800001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorErdoğan, Serkan
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofAnatomia Histologia Embryologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjecthormone
dc.subjectimmunohistochemistry
dc.subjectsheep
dc.subjecttongue
dc.subjectMajor Salivary-Glands
dc.subjectSkeletal-Muscle
dc.subjectReceptor Expression
dc.subjectAdipose-Tissue
dc.subjectCells
dc.subjectGene
dc.subjectIdentification
dc.subjectProliferation
dc.subjectPancreas
dc.subjectPeptide
dc.titleThe expressions of some metabolic hormones (leptin, ghrelin and obestatin) in the tissues of sheep tongue
dc.typeArticle

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