Comparison of intravenous paracetamol and tramadol for postoperative analgesia in patients with septo-rhinoplasty
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Dosyalar
Tarih
2011
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Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: The aim of the study was to compare the efficacy of i.v. tramadol and i.v. paracetamol for postoperative analgesia after septo-rhinoplasty operation. Method: Fifty American Society of Anesthesiology (ASA) physical status I-II patients, aged between 18-50, receiving septo-rhinoplasty operation are included in the study. The patients were randomly divided into two groups for postoperative analgesia. In Group I; i.v. paracetamol 1 gr was infused 30 minutes before the end of the operation. In Group II; i.v. tramadol 1 mg kg -1 was given 20 minutes before the end of the operation. A blinded observer recorded the pain intensity, analgesic need, patient satisfaction and side effects of drugs for postoperative at 1 h, 6 h and 24 h hours. Results: The VAS values are similar in both groups at postoperative 1st hour, no statistically significant differences were found (p> 0.05). VAS values for group II were significantly lower than group 1 at 6 h and 24 h postoperatively (p< 0.05). No serious side-effects were recorded during the study. The most frequent adverse effect was nausea (25%) in group II. No significant difference was found between groups in terms of vomiting (p>0.05), whereas the rate of nausea was significantly lower in group I than group II. Cortisol levels significantly decreased in both groups at postoperative period. Conclusion: Intravenous paracetamol administration provided adequate analgesia as opioids especially at early postoperative period for mild-moderate pain therapy in perioperative period.
Açıklama
Anahtar Kelimeler
Paracetamol, Postoperative pain, Tramadol, paracetamol, tramadol, adult, article, clinical article, drug efficacy, drug infusion, female, human, male, nausea, nose septum reconstruction, pain assessment, patient satisfaction, postoperative analgesia, postoperative pain, side effect, single blind procedure, visual analog scale, vomiting
Kaynak
Anestezi Dergisi
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
19
Sayı
4
