Novel binuclear antimony(III) halide complexes of 5-methoxy-2-mercaptobenzimidazole: synthesis, structural characterization, and biological studies

Basit Öğe Kaydı
dc.authorscopusid36785856200
dc.authorscopusid57192317122
dc.authorscopusid35363944400
dc.authorscopusid8235840100
dc.authorscopusid57196276440
dc.authorscopusid6602706096
dc.authorscopusid57212309470
dc.contributor.authorÖztürk, İbrahim İsmet
dc.contributor.authorYarar, Sinem
dc.contributor.authorGürgan, Muazzez
dc.contributor.authorCeyhan, Deniz
dc.contributor.authorPanagiotou, Nikos
dc.contributor.authorTasiopoulos, Anastasios J.
dc.contributor.authorAral, Cenk
dc.date.accessioned2022-05-11T14:02:46Z
dc.date.available2022-05-11T14:02:46Z
dc.date.issued2020
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümü
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Biyoloji Bölümü
dc.description.abstractThe new binuclear antimony(III) complexes corresponding to the formulas [SbCl3(µ2-S)(MtMBZIM)2]2 (1), {[SbBr2(µ2-Br)(MtMBZIM)2]2·H2O} (2) and {[SbI2(µ2-I)(MtMBZIM)2]2·H2O} (3) (MtMBZIM: 5-methoxy-2-mercaptobenzimidazole) have been synthesized and structurally characterized with regard to their melting point, elemental analysis, molar conductivity, FT-IR, and FT-Raman spectroscopic techniques, and TG-DTA analysis. The crystal structures of 1-3 have been determined by single-crystal X-ray diffraction. Compounds 1-3 are doubly bridged dimers and in each square pyramidal monomeric unit, the equatorial plane is formed by two sulfur and two halogen atoms in trans-S, trans-X arrangement. The monomeric units in 2 and 3 are linked to each other via halogen bridges, but in 1, they are linked to each other via sulfur bridges; to our knowledge, this binding type is the first example of trans-S, trans-X square pyramidal antimony(III) complexes. Newly synthesized complexes with their corresponding ligand have been tested for their in vitro cytotoxic activity against human adenocarcinoma cervix (HeLa) cells as well as for their antimicrobial activity. The influence of 1-3 on the catalytic peroxidation of the linoleic acid by the enzyme lipoxygenase (LOX) has been determined experimentally and theoretically. © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group.
dc.description.sponsorship17,096
dc.description.sponsorshipI.I.O. and S.Y. acknowledge the financial support from Tekirdag Namik Kemal University Scientific Research Project (Project No. NKUBAP.01.GA.17.096).
dc.identifier.doi10.1080/00958972.2020.1735003
dc.identifier.endpage505
dc.identifier.issn0095-8972
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85081294759
dc.identifier.scopusqualityQ3
dc.identifier.startpage485
dc.identifier.urihttps://doi.org/10.1080/00958972.2020.1735003
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4479
dc.identifier.volume73
dc.identifier.wosWOS:000519365100001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorÖztürk, İbrahim İsmet
dc.institutionauthorYarar, Sinem
dc.institutionauthorGürgan, Muazzez
dc.institutionauthorCeyhan, Deniz
dc.institutionauthorAral, Cenk
dc.language.isoen
dc.publisherTaylor and Francis Ltd.
dc.relation.ispartofJournal of Coordination Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectantimicrobial activity
dc.subjectAntimony(III) halide complexes
dc.subjectcrystal structures
dc.subjectcytotoxic activity
dc.subjectlipoxygenase inhibition
dc.titleNovel binuclear antimony(III) halide complexes of 5-methoxy-2-mercaptobenzimidazole: synthesis, structural characterization, and biological studies
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
4479.pdf
Boyut:
9.13 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Fen Edebiyat Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu