Histopathological Correlation of Squamous Cell Abnormalities Detected on Cervical Cytology

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dc.authorid0000-0002-4723-7297
dc.authorscopusid6506061779
dc.authorscopusid13807001000
dc.authorscopusid55362905300
dc.authorscopusid39760902600
dc.authorscopusid38361632800
dc.authorscopusid7801342819
dc.authorscopusid36954955300
dc.authorwosidBacanakgil, Besim Haluk/AAE-3936-2019
dc.contributor.authorAbalı, Remzi
dc.contributor.authorBacanakgil, Besim Haluk
dc.contributor.authorÇelik, Serdar
dc.contributor.authorAras, Özlem
dc.contributor.authorKoca, Pelin
dc.contributor.authorBoran, Birtan
dc.contributor.authorDursun, Nevra
dc.date.accessioned2022-05-11T14:35:50Z
dc.date.available2022-05-11T14:35:50Z
dc.date.issued2011
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractObjective: To investigate the correlation between cytology and cervical biopsy in patients with squamous cell abnormality on cervical cytology. Material and Method: The cervical smears diagnosed in our clinic between 2005-2008 were reviewed retrospectively. Cases which exhibited squamous cell abnormality (n: 374) were evaluated. Results: The mean age was 45.15 +/- 10.78. In the cytopathological results, 256 (68.4%) ASC-US, 21 (5.6%) ASC-H, 31 (8.2%) LSIL, 48 (12.8%) HSIL, and 8 (4.8%) invasive carcinomas were diagnosed. Histopathological results were 213 (57%) nonneoplastic, 85 (22.7%) CIN I, 14 (3.7%) CIN II, 34(9.0%) CIN III and 28 (7.5%) invasive squamous cell carcinomas. Including all squamous cell abnormalities, the sensitivity of the smear test in CIN I and higher grade lesions was 56.95% and the false positivity was 43.04%. Excluding ASC-US and ASC-H lesions, the sensitivity of the smear test was 77.31% and the false positivity was 22.68%. After evaluating cervical cyto-histopathological correlation, the positive predictive value was found to be 100% in invasive carcinoma, 62% in HSIL and 38% in LSIL. Conclusion: As the grade of cytopathological result increases, the correlation between biopsy and the smear test also increases. The high sensitivity of the cervical smear test for high-grade lesions shows that it is an effective screening test.
dc.identifier.doi10.5146/tjpath.2011.01063
dc.identifier.endpage148
dc.identifier.issn1018-5615
dc.identifier.issn1309-5730
dc.identifier.issue2en_US
dc.identifier.pmid21630201
dc.identifier.scopus2-s2.0-79957466398
dc.identifier.scopusqualityQ3
dc.identifier.startpage144
dc.identifier.urihttps://doi.org/10.5146/tjpath.2011.01063
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8250
dc.identifier.volume27
dc.identifier.wosWOS:000217439400010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAbalı, Remzi
dc.language.isoen
dc.publisherDe Gruyter Open Ltd
dc.relation.ispartofTurkish Journal of Pathology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCytology
dc.subjectCervical smears
dc.subjectPapanicolaou test
dc.subjectPathology
dc.titleHistopathological Correlation of Squamous Cell Abnormalities Detected on Cervical Cytology
dc.title.alternativeServikal sitolojide skuamöz hücre anormallikleri saptanan olgularda Histopatolojik Korelasyon]
dc.typeArticle

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