Assessment of Metabolic Syndrome Components in Patients with Normocalcemic Hyperparathyroidism: A Retrospective Study

Basit Öğe Kaydı
dc.contributor.authorBaykut, Osman Alp
dc.contributor.authorElbüken, Gülşah
dc.contributor.authorTokuç, Burcu
dc.contributor.authorZuhur, Sayid Shafi
dc.date.accessioned2023-05-06T17:19:34Z
dc.date.available2023-05-06T17:19:34Z
dc.date.issued2023
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıp Eğitimi Ana Bilim Dalı
dc.description.abstractObjective: Normocalcemic hyperparathyroidism is characterized by elevated parathormone levels persisting for 3 months or longer despite normal serum Ca levels. This study aimed to retrospectively compare the prevalence of individual metabolic syndrome components between patients with nor-mocalcemic hyperparathyroidism and an age-and sex-matched control group.Methods: Data of 82 normocalcemic hyperparathyroidism patients and 80 control subjects with nor-mal parathormone and calcium levels were reviewed retrospectively. Those meeting 3 or more of the 2001 metabolic syndrome diagnostic criteria of the US National Cholesterol Education Program Adult Treatment Panel III were considered as having metabolic syndrome. Also, Turkish waist circumfer-ence cutoff values were used to identify abdominal obesity and to estimate the metabolic syndrome frequency.Results: Considering that higher body mass index of normocalcemic patients would confound the analysis, analysis of covariance adjusted for body mass index was used to compare the groups, which showed increased waist circumference, waist/hip ratio, parathormone, 25 OH vitamin D3, fasting plasma glucose, and total cholesterol and low-density lipop rotei n-cho leste rol levels in normocal-cemic hyperparathyroidism patients than controls. The prevalence of metabolic syndrome among normocalcemic hyperparathyroidism patients was 32.9% (22.5% in controls) using the National Cholesterol Education Program Adult Treatment Panel III criteria versus 34.1% (23.8% in controls) using the Turkish waist circumference cutoff values.Conclusion: The percentage of patients meeting the metabolic syndrome criteria was higher com-pared to the control group. Even in the case of normocalcemic hyperparathyroidism, which is con-sidered to be a milder condition, the prevalence of metabolic syndrome was relatively higher than in the control group, suggesting that normocalcemic hyperparathyroidism may be a cardiovascular risk factor by predisposing to metabolic syndrome.
dc.description.sponsorship[2021.69.03.09]
dc.description.sponsorshipEthics Committee Approval: The study was approved by the Local Ethics Committee of Tekirda? Nam?k Kemal University, Faculty of Medicine (date: March 30, 2021, no: 2021.69.03.09) .
dc.identifier.doi10.5152/erp.2023.22156
dc.identifier.endpage14
dc.identifier.issn1301-2193
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85146819346
dc.identifier.scopusqualityQ4
dc.identifier.startpage8
dc.identifier.trdizinid1167776
dc.identifier.urihttps://doi.org/10.5152/erp.2023.22156
dc.identifier.urihttps://hdl.handle.net/20.500.11776/11864
dc.identifier.volume27
dc.identifier.wosWOS:001098169000003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorBaykut, Osman Alp
dc.institutionauthorElbüken, Gülşah
dc.institutionauthorTokuç, Burcu
dc.institutionauthorZuhur, Sayid Shafi
dc.language.isoen
dc.publisherAves
dc.relation.ispartofTurkish Journal Of Endocrinology And Metabolism
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBody mass index
dc.subjectmetabolic syndrome
dc.subjectnormocalcemic hyperparathyroidism
dc.subjectwaist cir-cumference
dc.subjectwaist
dc.subjecthip ratio
dc.subjectGlucose
dc.titleAssessment of Metabolic Syndrome Components in Patients with Normocalcemic Hyperparathyroidism: A Retrospective Study
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
11864.pdf
Boyut:
1.33 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu