Tiroid Nodüllerinde Malign ve Benign Ayrımında Difüzyon Ağırlıklı Manyetik Rezonans İncelemenin Yeri
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2019
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info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmanın amacı, Difüzyon Ağırlıklı Manyetik Rezonans Görüntülemenin (DAMRG) tiroid nodüllerinde malign-benign ayrımındaki yerini araştırmak idi.Materyal ve Metot: Çalışmaya tiroid nodülü ve patolojik tanısı olan 39 hasta ve 40 nodül dahil edildi. İzlenen nodüller, DAMRG ile incelendi ve elde edilen Apparent Diffusion Coefficient (ADC) değerleri ve patolojik sonuçlar arasındaki ilişki istatistiksel olarak değerlendirildi.Bulgular: Nodüllerin 9’u malign, 31’i benign karakterdeydi. Malign ve benign nodüllerin ortalama ADC değerleri sırasıyla (1,60±0,29)x10?³ sn/mm²)ve (2,14±0,39)x10?³ sn/mm²) bulundu. Malign ve benign nodüllerin ADC değerleri arasında anlamlı istatistiksel farklılık izlendi (p<0,001). Receiver Operator Coefficient (ROC) analizi ile malign nodüllerde cut-off değer 1,67x10?³ sn/mm² olarak hesaplandı.Sonuç: ADC değerleri, benign ve malign tiroid nodüllerini ayırmak için non-invaziv bir tanı metodu olarak kullanılabilir.
Aim: The aim of this study was to investigate the role of the Diffusion Weighted Imaging (DWI) sequences in diagnosis of malignant and benign nodules of thyroid nodules. Materials and Methods: Thirty nine patients and fourty nodules were enrolled to the study. The observed nodules were examined with DWI. Relationship between obtained Apparent Diffusion Coefficient (ADC) values and pathological results were statistically evaluated.. Results: There were 9 malignant and 31 benign nodules. Mean ADC values were evaluated (1.60±0.29)x10?³ sn/mm² for malignant, and (2.14±0.39)x10?³ sn/mm²) for benign nodules, respectively. There was a statistical difference between ADC values of malignant and benign nodules (p<0.001). The ADC cut-off value of malignant nodules was 1.67x10?³ sn/mm² with Receiver Operator Coefficient (ROC) analysis. Conclusion: ADC values might be used as a non-invasive diagnostic tool for discriminating the malignant and benign thyroid nodules.
Aim: The aim of this study was to investigate the role of the Diffusion Weighted Imaging (DWI) sequences in diagnosis of malignant and benign nodules of thyroid nodules. Materials and Methods: Thirty nine patients and fourty nodules were enrolled to the study. The observed nodules were examined with DWI. Relationship between obtained Apparent Diffusion Coefficient (ADC) values and pathological results were statistically evaluated.. Results: There were 9 malignant and 31 benign nodules. Mean ADC values were evaluated (1.60±0.29)x10?³ sn/mm² for malignant, and (2.14±0.39)x10?³ sn/mm²) for benign nodules, respectively. There was a statistical difference between ADC values of malignant and benign nodules (p<0.001). The ADC cut-off value of malignant nodules was 1.67x10?³ sn/mm² with Receiver Operator Coefficient (ROC) analysis. Conclusion: ADC values might be used as a non-invasive diagnostic tool for discriminating the malignant and benign thyroid nodules.
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