Evaluation of biopathogenesis of meningioma cases in the light of literature

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dc.authorscopusid56674583800
dc.authorscopusid55372092900
dc.authorscopusid57202435374
dc.authorscopusid6503989986
dc.authorscopusid7006006212
dc.contributor.authorKaraarslan, Numan
dc.contributor.authorGürbüz, Mehmet Sabri
dc.contributor.authorŞimşek, Abdullah Talha
dc.contributor.authorErşahin, M.
dc.contributor.authorBerkman, Mehmet Zafer
dc.date.accessioned2022-05-11T14:34:47Z
dc.date.available2022-05-11T14:34:47Z
dc.date.issued2018
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalı
dc.description.abstractIn this study, it was aimed to investigate the bio pathogenesis of the cases diagnosed with meningioma in the light of the literature. The patients (n=79) operated due to the meningioma in neurosurgery department between 2005 and 2010 were retrospectively examined. Findings that may affect the biological behavior and prognosis of the tumours recorded in these reported data were evaluated. A total of 79 cases meeting the research criteria were included in the study. When the histopathological grade of the cases was examined, it was seen that 59 cases (74.7%) were grade I and 20 cases (25.3%) were grade II. When the relation between the localization and histological grade of the cases was examined, it was determined that the meningiomas were most frequently located in convexity and that most of grade II cases were localized at this site. Preoperative peritumoral oedema was found to be more prevalent, especially in the sphenoid wing and convexity meningiomas. A total of 9 cases of recurrence (11.4%) occurred during follow-up period. When carrying out evaluation between surgical resection grade and recurrent cases, it was detected that all cases where it was performed Simpson grade IV and Kobayashi grade IVA and IVB resection had a recurrence. When the localization of recurrent cases was examined, it was seen that 4 cases (%44.4) were sphenoid wing meningioma, 2 cases (%22.2) were parasagittal meningioma, 1 case (%11.1) was tuberculosis sellae meningioma and 1 case (%11.1) was int-raventricular meningioma. In our study, histopathologic subtype and surgical resection grade were found to play a significant role in prognosis in meningiomas. It was also thought that the presence of peritumoral oedema and tumour localization could affect the biological behavior and prognosis of the meningioma. Findings obtained should be supported by multi-center studies that will include the cases of different races with more series. © 2018, Logos Medical Publishing. All rights reserved.
dc.identifier.doi10.5222/MMJ.2018.77905
dc.identifier.endpage118
dc.identifier.issn2149-2042
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85048323601
dc.identifier.scopusqualityQ4
dc.identifier.startpage112
dc.identifier.urihttps://doi.org/10.5222/MMJ.2018.77905
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8094
dc.identifier.volume33
dc.indekslendigikaynakScopus
dc.institutionauthorKaraarslan, Numan
dc.institutionauthorŞimşek, Abdullah Talha
dc.language.isotr
dc.publisherLogos Medical Publishing
dc.relation.ispartofMedeniyet Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiopathogenesis
dc.subjectHistopathology
dc.subjectMeningioma
dc.titleEvaluation of biopathogenesis of meningioma cases in the light of literature
dc.title.alternativeMeningiom olgularının biyopatogenezinin literatür eşliğinde değerlendirilmesi
dc.typeArticle

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