Evaluation of Empirical Antibiotic Treatment in Culture Negative Pyogenic Vertebral Osteomyelitis

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dc.authorid0000-0003-2003-6337
dc.authorid0000-0001-5590-0637
dc.authorscopusid57196589837
dc.authorscopusid57202435374
dc.authorscopusid35197435300
dc.authorscopusid56674583800
dc.authorwosidErtan, Asli/AAE-6201-2021
dc.authorwosidYILMAZ, Ibrahim/H-6199-2019
dc.authorwosidKARAARSLAN, Numan/I-6819-2019
dc.contributor.authorDoğan, Mustafa
dc.contributor.authorŞimşek, Abdullah Talha
dc.contributor.authorYılmaz, İbrahim
dc.contributor.authorKaraarslan, Numan
dc.date.accessioned2022-05-11T14:12:26Z
dc.date.available2022-05-11T14:12:26Z
dc.date.issued2019
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalı
dc.description.abstractAIM: To investigate the efficacy of empirical antibiotic treatment in culture-negative pyogenic vertebral osteomyelitis (PVO) cases. MATERIAL and METHODS: The records of patients with culture-negative PVO who were treated at infectious diseases and neurosurgery outpatient clinics in the past four years were examined retrospectively. The control group comprised healthy subjects with similar age, gender, and body mass index but without pathology. The comparison of the groups was performed by analysis of variance. Statistical significance was accepted as p<0.05. RESULTS: No statistically significant difference in the white blood cell count and erythrocyte sedimentation rate was found between the spondylodiscitis and the healthy subject groups when the blood parameters obtained before and after the treatment (p>0.05). However, a statistical significance was assessed in the results of the comparison for C-reactive protein (p<0.05). CONCLUSION: In the context of evidence-based medicine and the rational use of antibiotics, it is clear that antibiotics should be preferred according to the culture antibiogram results in the treatment of infectious diseases.
dc.identifier.doi10.5137/1019-5149.JTN.25018-18.2
dc.identifier.endpage822
dc.identifier.issn1019-5149
dc.identifier.issue6en_US
dc.identifier.pmid31049918
dc.identifier.scopus2-s2.0-85075805429
dc.identifier.scopusqualityQ3
dc.identifier.startpage816
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.25018-18.2
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5552
dc.identifier.volume29
dc.identifier.wosWOS:000498868200004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDoğan, Mustafa
dc.institutionauthorKaraarslan, Numan
dc.language.isoen
dc.publisherTurkish Neurosurgical Soc
dc.relation.ispartofTurkish Neurosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEmpirical treatment
dc.subjectPyogenic vertebral osteomyelitis
dc.subjectRational antibiotic use
dc.subjectRational drug use
dc.subjectSpondylodiscitis
dc.titleEvaluation of Empirical Antibiotic Treatment in Culture Negative Pyogenic Vertebral Osteomyelitis
dc.typeArticle

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