Effectiveness of the diagnostic pathway of BLES: could it be safely used as a therapeutic method in selected benign Lesions?

Basit Öğe Kaydı
dc.authorid0000-0002-6396-3168
dc.authorscopusid56085483700
dc.authorscopusid8204207500
dc.authorscopusid15844109600
dc.authorscopusid56084894100
dc.authorscopusid55915823300
dc.authorscopusid37058172000
dc.authorwosidGurdal, Sibel Ozkan/ABA-3882-2020
dc.authorwosidÖZÇAĞLAYAN, ÖMER/ABA-4293-2020
dc.authorwosidOzcaglayan, Tugba İlkem Kurtoglu/ABA-4247-2020
dc.contributor.authorKurtoğlu Özçağlayan, Tuğba İlkem
dc.contributor.authorGürdal, Sibel Özkan
dc.contributor.authorÖznur, Meltem
dc.contributor.authorÖzçağlayan, Ömer
dc.contributor.authorDoğru, Mücahit
dc.contributor.authorTopçu, Birol
dc.date.accessioned2022-05-11T14:07:44Z
dc.date.available2022-05-11T14:07:44Z
dc.date.issued2019
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik Ana Bilim Dalı
dc.description.abstractPURPOSE In this study, we aimed to investigate the breast lesion excision system (BLES) as a tool and a practical alternative technique to surgical biopsy and other percutaneous biopsy methods for spicious lesions. We also wanted to share our initial experience with BLES and compare it with standard percutaneous biopsy methods. METHODS From July 2015 to December 2016, a total of 50 patients who had high-risk lesions which were diagnosed with core needle biopsy (CNB) or had lesions with radiology pathology discordance, or had high-risk factors, high-grade anxiety, or suspicious follow-up lesions were enrolled in the study.These lesions were classified as Breast Imaging Reporting and Data System (BI-BADS) 3 or 4, which are under 2 cm. Pathologic diagnoses before and after BLES were evaluated comparatively. The diagnostic and therapeutic success and the complications of CNB and BLES were analyzed. RESULTS After BLES, two cases were diagnosed as atypical lobular hyperplasia and atypical ductal hyperplasia. Since the surgical margin was negative, re-excision was not required. Two cases were diagnosed as malignant, and no residual tissue was detected in the operation region. Total excision rates were reported as 56%. Minor hematoma was observed in only 1 out of 50 cases (2%), and spontaneous remission was observed. Two patients (4%) complained of pain during the procedure. Radiofrequency-related thermal damage to the specimen showed: Grade 0 (<0.5 mm) damage in 88%, Grade 1 (0.5-1.5 mm) in 10%, Grade 2 (>1.5 mm or thermal damage in diffuse areas) in 2%, and Grade 3 (diffuse thermal damage or inability to diagnose) in 0%. We found a significant positive correlation between classification of thermal damage and lesion fat cell content (r = 0.345, P = 0.015). CONCLUSION BLES is a safe technique that can be effectively used with low complication rates in the excision of benign and high-risk breast lesions in selected cases. It may also provide high diagnostic success and even serve as a therapeutic method in high-risk lesions, such as radial scar, papilloma, and atypical lobular hyperplasia with high complete excision rates without fragmentation of lesions.
dc.identifier.doi10.5152/dir.2019.18427
dc.identifier.endpage434
dc.identifier.issn1305-3612
dc.identifier.issue6en_US
dc.identifier.pmid31650964
dc.identifier.scopus2-s2.0-85074552605
dc.identifier.scopusqualityQ2
dc.identifier.startpage428
dc.identifier.urihttps://doi.org/10.5152/dir.2019.18427
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5186
dc.identifier.volume25
dc.identifier.wosWOS:000495398900003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKurtoğlu Özçağlayan, Tuğba İlkem
dc.institutionauthorGürdal, Sibel Özkan
dc.institutionauthorÖznur, Meltem
dc.institutionauthorÖzçağlayan, Ömer
dc.institutionauthorDoğru, Mücahit
dc.institutionauthorTopçu, Birol
dc.language.isoen
dc.publisherTurkish Soc Radiology
dc.relation.ispartofDiagnostic and Interventional Radiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectExcision System Bles
dc.subjectNonpalpable Breast-Lesions
dc.subjectBiopsy
dc.subjectSpecimen
dc.subjectRadiofrequency
dc.subjectDevice
dc.subjectRisk
dc.titleEffectiveness of the diagnostic pathway of BLES: could it be safely used as a therapeutic method in selected benign Lesions?
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
5186.pdf
Boyut:
391.13 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu