Neutrophil/lymphocyte ratio in obese adolescents

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dc.authorid0000-0002-4060-0583
dc.authorid0000-0001-5992-9488
dc.authorwosidDonma, Mustafa Metin/ABF-2169-2021
dc.authorwosidDonma, Orkide/AAI-1853-2019
dc.authorwosidDonma, Metin/AAB-6079-2020
dc.authorwosidYilmaz, Ahsen/ABB-1083-2021
dc.contributor.authorAydın, Murat
dc.contributor.authorYılmaz, Ahsen
dc.contributor.authorDonma, Mustafa Metin
dc.contributor.authorTülübaş, Feti
dc.contributor.authorDemirkol, Muhammed
dc.contributor.authorErdoğan, Murat
dc.contributor.authorGürel, Ahmet
dc.date.accessioned2022-05-11T14:12:36Z
dc.date.available2022-05-11T14:12:36Z
dc.date.issued2015
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractOBJECTIVE: Obesity is a growing health problem in most of the developed countries. It is associated with many chronic diseases, affecting particularly endocrine and cardiovascular systems. Inflammation plays a key role in pathophysiology of obesity. In this study, we aimed to investigate the inflammation status in obese children using neutrophil/lymphocyte ratio. METHODS: In this study 130 obese and 57 healthy children were assessed retrospectively. According to Centers for Disease Control 2000 (CDC) BMI percentiles for childhood and adulthood, 85-95 percentile was considered as overweight and >95 percentile as obese. RESULTS: Lymphocyte/neutrophil ratios in the obese group were significantly higher compared to those in healthy controls (p = 0.03 and p = 0.045, respectively). Neutrophil/lymphocyte ratio and CRP level in the obese group were significantly higher compared to those in healthy controls (p = 0.02 and p = 0.00, respectively). Thrombocyte/lymphocyte ratios were not significantly different between two groups (p = 0.156). CONCLUSION: It is possible that childhood obesity which has been increasingly prevalent recently triggers the pathogenesis of atherosclerosis during the early years of life. Increased neutrophil/lymphocyte ratio might be associated with the severity of inflammation which plays a role in the early stages of atherosclerosis. Therefore, taking childhood obesity under control using diet and other treatment methods will prevent mortality and morbidity in the elderly.
dc.identifier.doi10.14744/nci.2015.25238
dc.identifier.endpage91
dc.identifier.issn2148-4902
dc.identifier.issue2en_US
dc.identifier.pmid28058347
dc.identifier.startpage87
dc.identifier.urihttps://doi.org/10.14744/nci.2015.25238
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5610
dc.identifier.volume2
dc.identifier.wosWOS:000439921700001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorAydın, Murat
dc.institutionauthorYılmaz, Ahsen
dc.institutionauthorDonma, Mustafa Metin
dc.institutionauthorTülübaş, Feti
dc.institutionauthorDemirkol, Muhammed
dc.institutionauthorErdoğan, Murat
dc.institutionauthorGürel, Ahmet
dc.language.isoen
dc.publisherKare Publ
dc.relation.ispartofNorthern Clinics of Istanbul
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChildhood obesity
dc.subjectinflammation
dc.subjectneutrophil/lymphocyte ratio
dc.subjectNeutrophil-Lymphocyte Ratio
dc.subjectMean Platelet Volume
dc.subjectCardiovascular-Disease
dc.subjectInsulin-Resistance
dc.subjectAdipose-Tissue
dc.subjectAssociation
dc.subjectOverweight
dc.subjectChildren
dc.subjectAtherosclerosis
dc.subjectYoung
dc.titleNeutrophil/lymphocyte ratio in obese adolescents
dc.typeArticle

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