Neutrophil/lymphocyte ratio in obese adolescents
Yükleniyor...
Dosyalar
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Kare Publ
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
OBJECTIVE: Obesity is a growing health problem in most of the developed countries. It is associated with many chronic diseases, affecting particularly endocrine and cardiovascular systems. Inflammation plays a key role in pathophysiology of obesity. In this study, we aimed to investigate the inflammation status in obese children using neutrophil/lymphocyte ratio. METHODS: In this study 130 obese and 57 healthy children were assessed retrospectively. According to Centers for Disease Control 2000 (CDC) BMI percentiles for childhood and adulthood, 85-95 percentile was considered as overweight and >95 percentile as obese. RESULTS: Lymphocyte/neutrophil ratios in the obese group were significantly higher compared to those in healthy controls (p = 0.03 and p = 0.045, respectively). Neutrophil/lymphocyte ratio and CRP level in the obese group were significantly higher compared to those in healthy controls (p = 0.02 and p = 0.00, respectively). Thrombocyte/lymphocyte ratios were not significantly different between two groups (p = 0.156). CONCLUSION: It is possible that childhood obesity which has been increasingly prevalent recently triggers the pathogenesis of atherosclerosis during the early years of life. Increased neutrophil/lymphocyte ratio might be associated with the severity of inflammation which plays a role in the early stages of atherosclerosis. Therefore, taking childhood obesity under control using diet and other treatment methods will prevent mortality and morbidity in the elderly.
Açıklama
Anahtar Kelimeler
Childhood obesity, inflammation, neutrophil/lymphocyte ratio, Neutrophil-Lymphocyte Ratio, Mean Platelet Volume, Cardiovascular-Disease, Insulin-Resistance, Adipose-Tissue, Association, Overweight, Children, Atherosclerosis, Young
Kaynak
Northern Clinics of Istanbul
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
2
Sayı
2
