Comparison of the development of mouse embryos manipulated with different biopsy techniques

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dc.authorid0000-0002-1140-8058
dc.authorid0000-0002-2789-0635
dc.authorscopusid41862429400
dc.authorscopusid23767133200
dc.authorscopusid6602400461
dc.authorscopusid55919600100
dc.authorscopusid6603553213
dc.authorwosidBAĞIŞ/V-3827-2017
dc.authorwosidarat, sezen/ABA-7370-2020
dc.authorwosidSagirkaya, Hakan/AAH-8821-2021
dc.contributor.authorTaşkın, Ali Cihan
dc.contributor.authorAkkoç, Tolga
dc.contributor.authorSağırkaya, Hakan
dc.contributor.authorBağış, Haydar
dc.contributor.authorArat, Sezen
dc.date.accessioned2022-05-11T14:45:24Z
dc.date.available2022-05-11T14:45:24Z
dc.date.issued2016
dc.departmentFakülteler, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümü
dc.description.abstractPreimplantation genetic diagnosis is the detection of inherited diseases and the sex of embryos before implantation in the practice of human medicine as well as in veterinary medicine. The introduction of experimental animal embryo biopsy techniques has been a milestone in the developmental process of preimplantation genetic diagnosis techniques. The aim of the present study was to evaluate in vivo and in vitro development of embryos after biopsy in an experimental mouse model and to perform comparisons across different biopsy techniques (blastomere biopsy and trophectoderm biopsy). At the end of the study, no significant difference was observed between the blastomere biopsy group and the control group in terms of in vitro development, embryo quality, and fetal development, whereas embryo quality and in vivo development were negatively affected in the trophectoderm biopsy group (P < 0.05).
dc.description.sponsorshipTUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [KAMAG-107G027]
dc.description.sponsorshipThis research was supported by grant number KAMAG-107G027 from TUBITAK.
dc.identifier.doi10.3906/vet-1506-63
dc.identifier.endpage162
dc.identifier.issn1300-0128
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84957542231
dc.identifier.scopusqualityQ3
dc.identifier.startpage157
dc.identifier.urihttps://doi.org/10.3906/vet-1506-63
dc.identifier.urihttps://hdl.handle.net/20.500.11776/10031
dc.identifier.volume40
dc.identifier.wosWOS:000369159000005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorArat, Sezen
dc.language.isoen
dc.publisherScientific Technical Research Council Turkey-Tubitak
dc.relation.ispartofTurkish Journal of Veterinary & Animal Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMouse
dc.subjectembryo
dc.subjectbiopsy
dc.subjectblastomere
dc.subjectmicroblade
dc.subjecttrophectoderm
dc.subjectPreimplantation Genetic Diagnosis
dc.subjectTrophectoderm Biopsy
dc.subjectBlastomeres
dc.subjectPcr
dc.titleComparison of the development of mouse embryos manipulated with different biopsy techniques
dc.typeArticle

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