Poly(amidoamine) (PAMAM): An emerging material for electrochemical bio(sensing) applications
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Dosyalar
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Poly(amidoamine) (PAMAM) dendrimers have received attention due to their large surface areas with high concentration of functional end groups to bind biological material. They are monodisperse and hyper-branched polymers which include active functional groups outside its surface. These functional groups have been used for immobilizing the biorecognition molecules. They act as bioconjugating reagents and they have various applications in the fields of chemical and biochemical biosensors. Electrochemical techniques (amperometric, impedimetric, potentiometric, electrochemiluminescence) are useful for the determination of target molecules, with high sensitivity and selectivity. Dendrimer-modified enzyme biosensors, DNA biosensors, immunosensors and chemical sensors have been fabricated by using PAMAM dendrimer. This review provides a brief description of PAMAM dendrimers and its applications in biosensors and sensors. These sensors' limit of detection values are also compared in detail. Also this is the first review that assesses PAMAM dendrimers from the point of its usability in biosensor and sensor technologies. (C) 2015 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Poly(amidoamine), PAMAM, Electrochemical biosensor, Chemical sensor, Biosensing, Walled Carbon Nanotubes, Self-Assembled Monolayers, Modified Gold Surfaces, Dna Hybridization, Polyamidoamine Dendrimers, Impedimetric Detection, Alpha-Fetoprotein, Electrochemiluminescence Detection, Metal Nanoparticles, Graphene Oxide
Kaynak
Talanta
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
148
