Do we really need to coat the novel silicone intranasal splints with antibiotics?

Basit Öğe Kaydı
dc.authorid0000-0002-5053-4276
dc.authorid0000-0003-3307-085X
dc.authorscopusid55078843000
dc.authorscopusid57188862011
dc.authorscopusid57188868231
dc.authorscopusid27968034900
dc.authorscopusid15055538600
dc.authorscopusid26648338400
dc.authorwosidKURÇ, Mine AYDIN/ABA-8088-2020
dc.authorwosidCiftci, Zafer/AAW-9972-2021
dc.contributor.authorÇiftçi, Zafer
dc.contributor.authorKurc, Mine Aydin
dc.contributor.authorKaya, Ayşe Demet
dc.contributor.authorSaraçoğlu Varol, Gamze
dc.contributor.authorDeniz, Mahmut
dc.contributor.authorGültekin, Erdoğan
dc.date.accessioned2022-05-11T14:12:39Z
dc.date.available2022-05-11T14:12:39Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun ve Boğaz Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Halk Sağlığı Ana Bilim Dalı
dc.description24th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) -- MAY 10-13, 2014 -- Barcelona, SPAIN
dc.description.abstractPurpose: The novel silicone intranasal splints are suggested to resist biofilm formation due to their surface characteristics. We aimed to ascertain the necessity of coating these splints with antibiotics to prevent splint associated infections, in vitro. Materials and methods: Pieces of Doyle II airway nasal splints made of medical grade silicone were divided into two test groups, treated with either (i) 0.2% nitrofurazone solution or (ii) 0.2% nitrofurazone containing ointment, and a control group, treated with (iii) 0.9% saline. Splint pieces were then incubated with Staphylococcus aureus solutions at 37 degrees C for 48 and 96 h. Following this, the splint pieces were incubated in 20 ml Mueller Hinton agar and appearing colonies were counted. Results: Following 48 and 96 h of incubation, the colonization rates in the saline group were significantly higher than the nitrofurazone ointment group (p < 0.001). The colonization rates in the liquid nitrofurazone group were significantly lower in comparison to the nitrofurazone ointment group (p < 0.001 and p = 0.019 respectively). Conclusions: The method of coating the splints with antibiotic was superior to using uncoated splints in terms of preventing S. aureus colonization. The rather smooth surfaces of the splints were insufficient to block bacterial colonization and coating them with antibiotics seems to be beneficial for the prevention of infections. (C) 2016 Elsevier Inc. All rights reserved.
dc.identifier.doi10.1016/j.amjoto.2016.02.007
dc.identifier.endpage451
dc.identifier.issn0196-0709
dc.identifier.issn1532-818X
dc.identifier.issue5en_US
dc.identifier.pmid27105976
dc.identifier.scopus2-s2.0-84963954623
dc.identifier.scopusqualityQ1
dc.identifier.startpage447
dc.identifier.urihttps://doi.org/10.1016/j.amjoto.2016.02.007
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5627
dc.identifier.volume37
dc.identifier.wosWOS:000384277600009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇiftçi, Zafer
dc.institutionauthorKurc, Mine Aydin
dc.institutionauthorSaraçoğlu Varol, Gamze
dc.institutionauthorDeniz, Mahmut
dc.institutionauthorGültekin, Erdoğan
dc.language.isoen
dc.publisherW B Saunders Co-Elsevier Inc
dc.relation.ispartofAmerican Journal of Otolaryngology
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectToxic-Shock-Syndrome
dc.subjectNasal Splints
dc.subjectBacterial-Colonization
dc.subjectSeptal Splints
dc.subjectSurgery
dc.subjectDecolonization
dc.subjectPrevalence
dc.subjectMorbidity
dc.subjectAdhesion
dc.subjectEfficacy
dc.titleDo we really need to coat the novel silicone intranasal splints with antibiotics?
dc.typeConference Object

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
5627.pdf
Boyut:
301.54 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu