Identification of novel single nucleotide polymorphisms in the growth hormone (GH) gene in Anatolian water buffalo (Bubalus bubalis) populations in Turkey

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dc.authorscopusid8431541400
dc.authorscopusid57200696504
dc.authorscopusid6701528877
dc.contributor.authorÖzkan Ünal, Emel
dc.contributor.authorIşık, Raziye
dc.contributor.authorSoysal, Mehmet İhsan
dc.date.accessioned2022-05-11T14:02:55Z
dc.date.available2022-05-11T14:02:55Z
dc.date.issued2020
dc.departmentFakülteler, Ziraat Fakültesi, Zootekni Bölümü
dc.departmentFakülteler, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümü
dc.description.abstractThis study was conducted to investigate the growth hormone (GH; somatotropin-like) gene polymorphisms in 150 water buffalo (Bubalus bubalis) from different regions of Turkey. 404 bp long partial intron 4, exon 5, 3’ UTR regions of the GH gene (also called GH/AluI locus) and 347 bp long exon-intron 3 and partial exon 4 regions of the GH gene (also called GH/MspI locus) were amplified, and their PCR products analyzed via DNA sequencing method. Seven genotypes due to twenty single nucleotide polymorphisms (SNP) and one deletion/insertion were identified in a 347 bp long region of the GH/MspI locus. A missense mutation from glycine to glutamate amino acid and four silent mutations in the serine, threonine, and asparagine amino acids were determined in the exon 3 region of the GH gene. Four genotypes due to eight SNP were identified in a 404 bp long region of the GH/AluI locus. A missense mutation from lysine to arginine amino acid and six silent mutations in Leucine, aspartate, histidine, lysine, arginine, and cysteine amino acids were revealed in the exon 5 region of the GH gene. The partial DNA sequence of the GH gene in water buffalos was reported, and these sequences were deposited at the NCBI Genbank database with the accession numbers MN266903-MN266909 and MN530973-MN530976. These SNP may have an effect on economic (such as body composition) and carcass traits, reproduction, and milk yield and content in water buffalo populations and may prove to be useful for water buffalo breeding. © 2020 All Rights Reserved
dc.description.sponsorshipAR.14.32, NKUBAP.00.24; Tarimsal Araştirmalar ve Politikalar Genel Müdürlüğü, Türkiye Cumhuriyeti Tarim Ve Orman Bakanliği: TAGEM ??AR -GE/ ??
dc.description.sponsorshipThis research was supported by the Scientific Research Projects Coordination Unit of Nam?k Kemal University, under project number NKUBAP.00.24.AR.14.32, and the Republic of Turkey Ministry of Agriculture and Forestry General Directorate of Agricultural Research and Policies, under project number TAGEM 13/AR-GE/29.
dc.description.sponsorshipThis research was supported by the Scienti ?ic Research Projects Coordination Unit of Namık Kemal University, under project number NKUBAP. ??????AR. ?????? and the Republic of Turkey Ministry of Agriculture and Forestry General Directorate of Agricultural Research and Policies, under project number TAGEM ??AR -GE/ ???
dc.identifier.doi10.37496/RBZ4920190260
dc.identifier.issn1516-3598
dc.identifier.scopus2-s2.0-85099507956
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.37496/RBZ4920190260
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4537
dc.identifier.volume49
dc.identifier.wosWOS:000596783300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorÖzkan Ünal, Emel
dc.institutionauthorIşık, Raziye
dc.institutionauthorSoysal, Mehmet İhsan
dc.language.isoen
dc.publisherSociedade Brasileira de Zootecnia
dc.relation.ispartofRevista Brasileira de Zootecnia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectbiodiversity
dc.subjectbreeding
dc.subjectDNA sequencing
dc.subjectgrowth traits
dc.titleIdentification of novel single nucleotide polymorphisms in the growth hormone (GH) gene in Anatolian water buffalo (Bubalus bubalis) populations in Turkey
dc.typeArticle

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