Aortic Pressures, Stiffness and Left Ventricular Function in Coronary Slow Flow Phenomenon
Yükleniyor...
Dosyalar
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Karger
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Coronary slow flow (CSF) phenomenon is characterized by delayed opacification of coronary vessels in a normal coronary angiogram. Although clinical and pathological features have been previously described, the underlying pathophysiology has not been fully elucidated. In this study, we aimed to evaluate central aortic pressure, aortic stiffness and left ventricular (LV) function in patients with coronary slow flow. Method and Results: The study population consisted of 154 patients who underwent coronary angiography because of typical and quasi-typical symptoms of angina. 81 patients with angiographically proven CSF and 73 cases with normal coronary flow pattern with similar risk profiles were enrolled in the study. Aortic pressures and indexes of elastic properties were evaluated using invasive methods. Aortic pulse pressure (mm Hg) and pulsality index of patients with CSF were found to be significantly higher than those of controls (60.8 +/- 13.8 vs. 53.7 +/- 14.5, p = 0.002; 0.84 +/- 0.22 vs. 0.67 +/- 0.18, p = 0.0001, respectively). LV Doppler parameters were deteriorated in patients with CSF. Aortic fractional pulse pressure and pulsality index were significantly correlated with the mean TIMI frame count and LV diastolic parameters in correlation analysis. Conclusion: The present findings allow us to conclude that impaired aortic elasticity in patients with CSF may also be responsible for the impaired LV diastolic parameters. Copyright (C) 2010 S. Karger AG, Basel
Açıklama
Anahtar Kelimeler
Aortic stiffness, Coronary slow flow, Diastolic dysfunction, Pulse pressure, Pulse-Wave Velocity, Cardiovascular Mortality, Independent Predictor, Hypertensive Patients, Endothelial Function, Diastolic Function, Artery-Disease, Atherosclerosis, Perfusion, Doppler
Kaynak
Cardiology
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
116
Sayı
4
