ASSESSMENT OF THE RELATIONSHIP BETWEEN PREDIABETES AND LOW MUSCLE MASS BASED ON BLOOD CREATININE LEVEL

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dc.authorscopusid57192706564
dc.authorscopusid56940716100
dc.authorscopusid57310710500
dc.authorscopusid56940845900
dc.authorscopusid57211719864
dc.authorscopusid55881189500
dc.contributor.authorIbragimova, S.I.
dc.contributor.authorNuskabayeva, G.O.
dc.contributor.authorShalkharova, Z.N.
dc.contributor.authorSadykova, K.Zh.
dc.contributor.authorJunusbekova, G.A.
dc.contributor.authorOran, M.
dc.date.accessioned2023-04-20T08:05:57Z
dc.date.available2023-04-20T08:05:57Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractBACKGROUND: Low muscle mass increases the risk of developing type 2 diabetes mellitus (DM 2) and prediabetes. Nutrition is an important factor in the study of the relationship between low muscle mass and the development of glucose metabolic disorders. AIM: The present study was conducted to assess the relationship between prediabetes and low muscle mass on the basis of serum creatinine levels, taking into account patient nutrition. MATERIALS AND METHODS: The study included 551 patients aged 18–69 years without DM 2. The glucose level was determined based on fasting glucose and after an oral glucose tolerance test (OGTT). Hyperglycemia is assessed according to the classification of the World Health Organization. The MedDietScore questionnaire was used to assess the nutritional factor, which determines the adherence of patients to the Mediterranean diet. In order to assess odds ratios (OR) and 95% confidence interval (CI), a binary logistic regression was performed. RESULTS: The prevalence of prediabetes in the group with the lowest and highest blood creatinine level was 31.9% and 17.5% respectively (p=0.016). As a result of the conducted regression analysis, a statistically significant relationship was found between low creatinine levels and the chances of having prediabetes (crude OR 2,07, 95% CI 1,21; 3,56), which persisted after adjusting for socio-demographic, anthropometric factors, stress level and physical activity as well as muscle strength. After adding the data on MedDietScore to the statistical model, the revealed relationship was lost (p = 0.187). CONCLUSION: Low serum creatinine increases the chances of the presence of prediabet regardless of gender, age, body weight index, the volume of the hips, the ratio of the volume of the waist to growth, as well as physical activity, the level of stress and muscular power. However, the chances of the presence of prediabet do not differ in persons with low creatinine blood depending on the commitment to the Mediterranean diet among the population of those living in the Turkestan region. © 2022 Russian Association of Endocrinologists. All rights reserved.
dc.identifier.doi10.14341/DM12745
dc.identifier.endpage238
dc.identifier.issn2072-0351
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85137717540
dc.identifier.scopusqualityQ4
dc.identifier.startpage226
dc.identifier.urihttps://doi.org/10.14341/DM12745
dc.identifier.urihttps://hdl.handle.net/20.500.11776/11126
dc.identifier.volume25
dc.identifier.wosWOS:000924682100003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorOran, Mustafa
dc.language.isoru
dc.publisherRussian Association of Endocrinologists
dc.relation.ispartofDiabetes Mellitus
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcreatinine
dc.subjectMediterranean diet
dc.subjectmuscle mass
dc.subjectprediabetes
dc.subjectprediabetic condition
dc.subjectcreatinine
dc.subjectglucose
dc.subjectadult
dc.subjectaged
dc.subjectanthropometric parameters
dc.subjectArticle
dc.subjectbody weight
dc.subjectclinical assessment
dc.subjectcreatinine blood level
dc.subjectfasting blood glucose level
dc.subjectfemale
dc.subjectgender
dc.subjecthip volume
dc.subjecthuman
dc.subjecthyperglycemia
dc.subjectimpaired glucose tolerance
dc.subjectlogistic regression analysis
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmeddietscore questionnaire
dc.subjectMediterranean diet
dc.subjectmuscle mass
dc.subjectmuscle strength
dc.subjectmuscle stress
dc.subjectnutrition
dc.subjectnutritional assessment
dc.subjectnutritional status
dc.subjectoral glucose tolerance test
dc.subjectpatient compliance
dc.subjectphysical activity
dc.subjectprevalence
dc.subjectsociodemographics
dc.subjectstatistical model
dc.subjectwaist volume to growth ratio
dc.subjectWorld Health Organization
dc.titleASSESSMENT OF THE RELATIONSHIP BETWEEN PREDIABETES AND LOW MUSCLE MASS BASED ON BLOOD CREATININE LEVEL
dc.typeArticle

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