Serum level of vitamin D in obstructive sleep apnea patients with fibromyalgia syndrome

dc.contributor.authorDumur, Seyma
dc.contributor.authorYıldırım, Tülay
dc.contributor.authorKucur, Mine
dc.contributor.authorAlp, Recep
dc.contributor.authorAydın, Murat
dc.date.accessioned2022-05-11T14:14:05Z
dc.date.available2022-05-11T14:14:05Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractObjectives: The aim of this study was to investigate the serum concentration of vitamin D in patients with obstructivesleep apnea syndrome (OSAS) alone and with coexisting fibromyalgia syndrome (FMS) and to assess the relationshipto pain.Methods: A total of 60 patients diagnosed with OSAS and 40 healthy individuals whose age and sex were analogousto the patient group were included in this study. The OSAS patients were examined for FMS according to the AmericanCollege of Rheumatology criteria, and 27 cases were identified. Group 1 consisted of patients with OSAS alone (n=33)and Group 2 comprised patients with FMS+OSAS (n=27). Serum samples were analyzed using an ultra-performanceliquid chromatography analyzer (Thermo Dionex Ultimate 3000; Thermo Fisher Scientific, Inc., Waltham, MA, USA).Results: A comparison of the OSAS and FMS+OSAS groups with the healthy individuals revealed that the vitamin Dlevel was significantly lower in the patient groups (Group 1: p=0.001, Group 2: p=0.038). No statistically significant difference was found in the vitamin D level between the subgroups of OSAS and FMS+OSAS. A weak negative correlationwas determined between the number of the tender points (r=-0.428) and the vitamin D level in the subjects with FMS(p=0.013). In addition, the oxygen desaturation values of the FMS+OSAS and OSAS patient groups were significantlydifferent (p=0.001).Conclusion: Patients with OSAS and FMS+OSAS had a low vitamin D level, which should be considered when planningtreatment strategies
dc.identifier.doi10.14744/ijmb.2020.44227
dc.identifier.endpage41
dc.identifier.issn2587-2362
dc.identifier.issn2618-642X
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85164313384
dc.identifier.scopusqualityN/A
dc.identifier.startpage36
dc.identifier.urihttps://doi.org/10.14744/ijmb.2020.44227
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TkRFM09UWTBOQT09
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5776
dc.identifier.volume4
dc.indekslendigikaynakScopus
dc.institutionauthorYıldırım, Tülay
dc.language.isoen
dc.relation.ispartofInternational Journal of Medical Biochemistry
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleSerum level of vitamin D in obstructive sleep apnea patients with fibromyalgia syndrome
dc.typeArticle

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