A NEW REAGENT FOR EFFICIENT SYNTHESIS OF NITRILES FROM ALDOXIMES USING METHOXYMETHYL BROMIDE
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Dosyalar
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Editura Acad Romane
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
This study outlines an efficient, high-yielding, and rapid method by which to access diverse nitriles from aldoximes with methoxymethyl bromide (MOM-Br) in THF. It represents the first application of MOM-Br as a deoximation reagent to synthesize nitriles. The reaction was performed at reflux to ensure excellent yield (79-96%) of the nitriles within 20-45 minutes. Furthermore, this method has been successfully applied to the synthesis of the synthesis precursor of aromatic, heteroaromatic, cyclic, and acyclic aliphatic.
Açıklama
Anahtar Kelimeler
aldoxime, nitriles, methoxymethyl bromide, dehydration, oximes, One-Pot Synthesis, Mom Ethers, Dehydration, Conversion, Amides, Deprotection, Anticancer, Cyanation, Catalyst, Oximes
Kaynak
Revue Roumaine De Chimie
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
64
Sayı
11
