A new reagent for efficient synthesis of nitriles from aldoximes using methoxymethyl bromide
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Dosyalar
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Editura Academiei Romane
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
This study outlines an efficient, high-yielding, and rapid method by which to access diverse nitriles from aldoximes with methoxymethyl bromide (MOM-Br) in THF. It represents the first application of MOM-Br as a deoximation reagent to synthesize nitriles. The reaction was performed at reflux to ensure excellent yield (79-96%) of the nitriles within 20-45 minutes. Furthermore, this method has been successfully applied to the synthesis of the synthesis precursor of aromatic, heteroaromatic, cyclic, and acyclic aliphatic. © 2019 Editura Academiei Romane. All rights reserved.
Açıklama
Anahtar Kelimeler
Kaynak
Revue Roumaine de Chimie
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
64
Sayı
11