A new reagent for efficient synthesis of nitriles from aldoximes using methoxymethyl bromide

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Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Editura Academiei Romane

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

This study outlines an efficient, high-yielding, and rapid method by which to access diverse nitriles from aldoximes with methoxymethyl bromide (MOM-Br) in THF. It represents the first application of MOM-Br as a deoximation reagent to synthesize nitriles. The reaction was performed at reflux to ensure excellent yield (79-96%) of the nitriles within 20-45 minutes. Furthermore, this method has been successfully applied to the synthesis of the synthesis precursor of aromatic, heteroaromatic, cyclic, and acyclic aliphatic. © 2019 Editura Academiei Romane. All rights reserved.

Açıklama

Anahtar Kelimeler

Kaynak

Revue Roumaine de Chimie

WoS Q Değeri

Scopus Q Değeri

Q4

Cilt

64

Sayı

11

Künye