Association between C-peptide level and microalbuminuria in patients with type 2 diabetes mellitus

dc.authorid0000-0001-7213-9624
dc.authorid0000-0001-7213-9624
dc.authorwosidBOYUK, BANU/ABA-7026-2021
dc.authorwosiderman, hande/AAZ-7697-2021
dc.authorwosidOkuturlar, Yildiz/X-3647-2018
dc.authorwosiderman, hande/AAP-6507-2021
dc.contributor.authorBoyuk, Banu
dc.contributor.authorOkuturlar, Yıldız
dc.contributor.authorUludag, Erdoğan
dc.contributor.authorAtalay, Hande
dc.contributor.authorGüzel, Savaş
dc.contributor.authorÇelebi, Aslan
dc.date.accessioned2022-05-11T14:42:06Z
dc.date.available2022-05-11T14:42:06Z
dc.date.issued2018
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractPurpose: Latest studies suggest that C-peptide may have a beneficial biological role on diabetic nephropathy. The aim of this study is to analyze whether there is an association between serum C-peptide level and microalbuminuria in type 2 diabetes mellitus (T2DM). Materials and Methods: We enrolled 184 T2DM patents and 46 healthy subjects in this study. Clinical variables and routine biochemical tests along with serum C peptide levels measured after an overnight fasting. Serum C peptide levels between 1.1 and 4.4 accepted as normal. 24-hour-urine samples were investigated and values between 30-300mgwere recorded as microalbuminuria. Pearson correlation analysis were used to determine associations between continuous variables. Results: C peptide levels were not significantly difference in T2DM patients compared to healthy controls. Serum C peptide levels showed positive correlation with insulin and microalbminuria with the Pearson correlation analysis. However, there was no significant association between other variables and C peptide levels. Conclusion: A correlation was found between microalbuminuria and serum C-peptide in this present study. Findings suggest C-peptide is related with renal complications of T2DM patients.
dc.identifier.doi10.17826/cumj.340257
dc.identifier.endpage61
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue1en_US
dc.identifier.startpage56
dc.identifier.urihttps://doi.org/10.17826/cumj.340257
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9221
dc.identifier.volume43
dc.identifier.wosWOS:000431893600009
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorGüzel, Savaş
dc.language.isoen
dc.publisherCukurova Univ, Fac Medicine
dc.relation.ispartofCukurova Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectC peptide
dc.subjectmicroalbuminuria
dc.subjectdiabetes
dc.subjectGlomerular-Filtration-Rate
dc.subjectRenal-Function
dc.subjectReactive Protein
dc.subjectPlasma
dc.titleAssociation between C-peptide level and microalbuminuria in patients with type 2 diabetes mellitus
dc.typeArticle

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