Association between C-peptide level and microalbuminuria in patients with type 2 diabetes mellitus

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Tarih

2018

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Cukurova Univ, Fac Medicine

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Purpose: Latest studies suggest that C-peptide may have a beneficial biological role on diabetic nephropathy. The aim of this study is to analyze whether there is an association between serum C-peptide level and microalbuminuria in type 2 diabetes mellitus (T2DM). Materials and Methods: We enrolled 184 T2DM patents and 46 healthy subjects in this study. Clinical variables and routine biochemical tests along with serum C peptide levels measured after an overnight fasting. Serum C peptide levels between 1.1 and 4.4 accepted as normal. 24-hour-urine samples were investigated and values between 30-300mgwere recorded as microalbuminuria. Pearson correlation analysis were used to determine associations between continuous variables. Results: C peptide levels were not significantly difference in T2DM patients compared to healthy controls. Serum C peptide levels showed positive correlation with insulin and microalbminuria with the Pearson correlation analysis. However, there was no significant association between other variables and C peptide levels. Conclusion: A correlation was found between microalbuminuria and serum C-peptide in this present study. Findings suggest C-peptide is related with renal complications of T2DM patients.

Açıklama

Anahtar Kelimeler

C peptide, microalbuminuria, diabetes, Glomerular-Filtration-Rate, Renal-Function, Reactive Protein, Plasma

Kaynak

Cukurova Medical Journal

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

43

Sayı

1

Künye