Identification and Characterization of Carnitine Palmitoyltransferase 1A (CPT1A) Gene in European Sea Bass (Dicentrarchus labrax)

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dc.contributor.authorGökçek, Emel Özcan
dc.contributor.authorIşık, Raziye
dc.date.accessioned2024-10-29T17:50:30Z
dc.date.available2024-10-29T17:50:30Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractObjective: CPT1A intervenes in the access of the long-chain fatty acyl-CoA to the mitochondrial matrix. In this study, we conducted the genetic polymorphisms of the partial sequence of the CPT1A gene in European sea bass (Dicentrarchus labrax) that were cage cultured in the Aegean Sea. Material and Methods: Genomic DNA was isolated from 100 European sea bass individuals. After amplifying a partial region of the CPT1A gene by thermal cycler, PCR products were sequenced via Sanger method. Results: We detected two SNPs in partial sequence of the CPT1A gene in European sea bass. TT, TA and AA genotypes were observed for CPT1A g.2080T>A locus with frequencies of 27.04, 49.92 and 23.04%, respectively. The frequencies of the g.2216A>G locus as AA, AG and GG were found to be 1.2, 19.58 and 79.21%, respectively. The CPT1A g.2080T>A locus was in HWE, whereas the g.2216A>G locus was not in HWE. Conclusion: European sea bass has a high commercial value. These findings suggest that two SNPs in the CPT1A gene could be used for genomic selection programs related to fatty acid composition in European sea bass. Keywords: Fatty acid, SNP, sea bass, variation
dc.identifier.doi10.29185/hayuretim.1261236
dc.identifier.endpage11
dc.identifier.issn1301-9597
dc.identifier.issn2645-9043
dc.identifier.issue1en_US
dc.identifier.startpage6
dc.identifier.trdizinid1207115
dc.identifier.urihttps://doi.org/10.29185/hayuretim.1261236
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1207115
dc.identifier.urihttps://hdl.handle.net/20.500.11776/13030
dc.identifier.volume64
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofHayvansal Üretim
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSNP
dc.subjectfatty acid
dc.subjectvariation
dc.subjectsea bass
dc.titleIdentification and Characterization of Carnitine Palmitoyltransferase 1A (CPT1A) Gene in European Sea Bass (Dicentrarchus labrax)
dc.typeArticle

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