The effect of Arnebia purpurea extract on the survival of random pattern skin flaps in rats

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dc.contributor.authorOrhan, Abdullah Erkan
dc.contributor.authorYüzbaşıoğlu Baran, Merve
dc.contributor.authorErol, Yağmur Reyhan
dc.contributor.authorBilensoy, Erem
dc.contributor.authorErdoğar, Nazlı
dc.contributor.authorDemirezer, Lütfiye Ömür
dc.contributor.authorKuruüzüm Uz, Ayşe
dc.date.accessioned2022-05-11T14:36:17Z
dc.date.available2022-05-11T14:36:17Z
dc.date.issued2018
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Plastik, Rekonstrüktif ve Estetik Cerrahi Ana Bilim Dalı
dc.description.abstractObjectives. One of the important causes of flap losses is ischemia-reperfusion damage. Arnebia species are rich in naphthoquinone derivatives which known to have anti-inflammatory and anti-oxidant effects. The aim of the present study was to investigate the effects of Arnebia purpurea extract on viability of the skin flaps. Methods. Eighteen Wistar rats were divided in three groups. Caudal-based 9×3 cm size skin flap was applied on dorsum of the all rats and following surgery, 2 cc of A. purpurea extract topically was applied to the group 1 and 2 cc of 0.2% Nitrofurazon cream topically was applied to the group 2, daily. The Group 3 only received flap surgery (control group). Seven days later, all subjects were euthanatized and necrosis rate in their flaps was calculated and compared to each other. Results. The necrosis rate was calculated as 20.25% ± 1.59% in Group 1, 32.05% ± 2.23% in the Group 2 and 37.33% ± 4.12% in the Group 3. It was found that necrosis rate in the Group 1 was statistically significantly less than Groups 2 and 3 (p < 0.001) and that difference in necrosis rate between Group 2 and Group 3 was not statistically significant (p > 0.05). Conclusion. Necrosis of skin flaps was reduced through topical application of A. purpurea extract.
dc.identifier.doi10.18621/eurj.335550
dc.identifier.endpage156
dc.identifier.issn2149-3189
dc.identifier.issn2149-3189
dc.identifier.issue3en_US
dc.identifier.startpage152
dc.identifier.trdizinidTWprek16STBOQT09
dc.identifier.urihttps://doi.org/10.18621/eurj.335550
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWprek16STBOQT09
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8431
dc.identifier.volume4
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorOrhan, Abdullah Erkan
dc.language.isoen
dc.relation.ispartofThe European Research Journal
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiyoloji
dc.subjectAlerji
dc.subjectAnatomi ve Morfoloji
dc.subjectAndroloji
dc.subjectAnestezi
dc.subjectOdyoloji ve Konuşma-Dil Patolojisi
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.subjectBiyofizik
dc.subjectBiyoteknoloji ve Uygulamalı Mikrobiyoloji
dc.subjectKalp ve Kalp Damar Sistemi
dc.subjectHücre Biyolojisi
dc.subjectKlinik Nöroloji
dc.subjectYoğun Bakım
dc.subjectTıp
dc.subjectDermatoloji
dc.subjectAcil Tıp
dc.subjectEndokrinoloji ve Metabolizma
dc.subjectGastroenteroloji ve Hepatoloji
dc.subjectGeriatri ve Gerontoloji
dc.subjectSağlık Bilimleri ve Hizmetleri
dc.subjectHematoloji
dc.subjectİmmünoloji
dc.subjectEnfeksiyon Hastalıkları
dc.subjectTamamlayıcı ve Entegre Tıp
dc.subjectTıbbi Etik
dc.subjectTıbbi İnformatik
dc.subjectTıbbi Laboratuar Teknolojisi
dc.subjectGenel ve Dahili Tıp
dc.subjectAdli Tıp
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectMikrobiyoloji
dc.subjectNörolojik Bilimler
dc.subjectKadın Hastalıkları ve Doğum
dc.subjectOnkoloji
dc.subjectGöz Hastalıkları
dc.subjectOrtopedi
dc.subjectKulak
dc.subjectBurun
dc.subjectBoğaz
dc.subjectPatoloji
dc.subjectPediatri
dc.subjectPeriferik Damar Hastalıkları
dc.subjectFizyoloji
dc.subjectTemel Sağlık Hizmetleri
dc.subjectPsikiyatri
dc.subjectHalk ve Çevre Sağlığı
dc.subjectRadyoloji
dc.subjectNükleer Tıp
dc.subjectTıbbi Görüntüleme
dc.subjectRehabilitasyon
dc.subjectSolunum Sistemi
dc.subjectRomatoloji
dc.subjectSpor Bilimleri
dc.subjectCerrahi
dc.subjectTransplantasyon
dc.subjectTropik Tıp
dc.subjectÜroloji ve Nefroloji
dc.titleThe effect of Arnebia purpurea extract on the survival of random pattern skin flaps in rats
dc.typeArticle

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