The effect of Arnebia purpurea extract on the survival of random pattern skin flaps in rats
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Dosyalar
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives. One of the important causes of flap losses is ischemia-reperfusion damage. Arnebia species are rich in naphthoquinone derivatives which known to have anti-inflammatory and anti-oxidant effects. The aim of the present study was to investigate the effects of Arnebia purpurea extract on viability of the skin flaps. Methods. Eighteen Wistar rats were divided in three groups. Caudal-based 9×3 cm size skin flap was applied on dorsum of the all rats and following surgery, 2 cc of A. purpurea extract topically was applied to the group 1 and 2 cc of 0.2% Nitrofurazon cream topically was applied to the group 2, daily. The Group 3 only received flap surgery (control group). Seven days later, all subjects were euthanatized and necrosis rate in their flaps was calculated and compared to each other. Results. The necrosis rate was calculated as 20.25% ± 1.59% in Group 1, 32.05% ± 2.23% in the Group 2 and 37.33% ± 4.12% in the Group 3. It was found that necrosis rate in the Group 1 was statistically significantly less than Groups 2 and 3 (p < 0.001) and that difference in necrosis rate between Group 2 and Group 3 was not statistically significant (p > 0.05). Conclusion. Necrosis of skin flaps was reduced through topical application of A. purpurea extract.
Açıklama
Anahtar Kelimeler
Biyoloji, Alerji, Anatomi ve Morfoloji, Androloji, Anestezi, Odyoloji ve Konuşma-Dil Patolojisi, Biyokimya ve Moleküler Biyoloji, Biyofizik, Biyoteknoloji ve Uygulamalı Mikrobiyoloji, Kalp ve Kalp Damar Sistemi, Hücre Biyolojisi, Klinik Nöroloji, Yoğun Bakım, Tıp, Dermatoloji, Acil Tıp, Endokrinoloji ve Metabolizma, Gastroenteroloji ve Hepatoloji, Geriatri ve Gerontoloji, Sağlık Bilimleri ve Hizmetleri, Hematoloji, İmmünoloji, Enfeksiyon Hastalıkları, Tamamlayıcı ve Entegre Tıp, Tıbbi Etik, Tıbbi İnformatik, Tıbbi Laboratuar Teknolojisi, Genel ve Dahili Tıp, Adli Tıp, Tıbbi Araştırmalar Deneysel, Mikrobiyoloji, Nörolojik Bilimler, Kadın Hastalıkları ve Doğum, Onkoloji, Göz Hastalıkları, Ortopedi, Kulak, Burun, Boğaz, Patoloji, Pediatri, Periferik Damar Hastalıkları, Fizyoloji, Temel Sağlık Hizmetleri, Psikiyatri, Halk ve Çevre Sağlığı, Radyoloji, Nükleer Tıp, Tıbbi Görüntüleme, Rehabilitasyon, Solunum Sistemi, Romatoloji, Spor Bilimleri, Cerrahi, Transplantasyon, Tropik Tıp, Üroloji ve Nefroloji
Kaynak
The European Research Journal
WoS Q Değeri
Scopus Q Değeri
Cilt
4
Sayı
3
