Plasma urotensin II and neurokinin B levels in acute myocardial infarction and stable coronary artery disease

Basit Öğe Kaydı
dc.authorscopusid26532378600
dc.authorscopusid16315021800
dc.authorscopusid6505680586
dc.authorscopusid36866111300
dc.authorscopusid7005837198
dc.authorscopusid55810763400
dc.authorscopusid56039778300
dc.authorwosidAlpsoy, Seref/Z-1808-2018
dc.contributor.authorAkkoyun, Dursun Çayan
dc.contributor.authorAkyüz, Aydın
dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorGürel, Ahmet
dc.contributor.authorGüler, Niyazi
dc.contributor.authorDeğirmenci, Hasan
dc.contributor.authorGurkan, Umit
dc.date.accessioned2022-05-11T14:10:11Z
dc.date.available2022-05-11T14:10:11Z
dc.date.issued2015
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractObjective: This aim of the study is to investigate whether there are possible plasma urotensin-II (U-II) and neurokinin B (NKB) level changes in patients with acute myocardial infarction (AMI) or not and plasma urotensin-II (U-II) and neurokinin B (NKB) level changes in patients with acute myocardial infarction (AMI) and stable coronary artery disease (CAD) and to evaluate whether there is any relationship between these changes and the pathogenesis of these diseases. Methods: This is a prospective case-control study. Three groups were formed from randomly admitted patients with AMI, stable CAD, and controls. Biochemical parameters and U-II and NKB levels were measured. Patients with congestive heart failure, chronic hepatic and renal failure, severe cardiac valve disease, and severe pulmonary hypertension were excluded from the study. The normality of the data was evaluated using the Kolmogorov-Smirnov test. We compared the three groups with one-way ANOVA and Tukey test (Kruskal-Wallis test and Mann-Whitney U test). Results: Compared with controls (n=31) and CAD patients (n=32), AMI patients (n=32) had lower U-II and NKB levels. In cases of stable CAD, U-II and NKB levels were similar. A positive correlation was found between U-II and NKB (r=0.720; p=0.000). U-II and NKB were poorly correlated with left ventricle ejection fraction but not with C-reactive protein. Conclusion: We found that U-II and NKB levels were lower in patients with AMI in than those with CAD or the control group. According to our findings, the decreased U-II and NKB levels were related to complicated atherosclerotic events.
dc.identifier.doi10.5152/akd.2014.5596
dc.identifier.endpage633
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue8en_US
dc.identifier.pmid25550175
dc.identifier.scopus2-s2.0-84940208520
dc.identifier.scopusqualityQ3
dc.identifier.startpage628
dc.identifier.urihttps://doi.org/10.5152/akd.2014.5596
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5320
dc.identifier.volume15
dc.identifier.wosWOS:000360292000008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAkkoyun, Dursun Çayan
dc.institutionauthorAkyüz, Aydın
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorGürel, Ahmet
dc.institutionauthorGüler, Niyazi
dc.institutionauthorDeğirmenci, Hasan
dc.institutionauthorGurkan, Umit
dc.language.isoen
dc.publisherTurkish Soc Cardiology
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjecturotensin II
dc.subjectneurokinin B
dc.subjectacute myocardial infarction
dc.subjectSubstance-P
dc.subjectIncreased Expression
dc.subjectPreeclampsia
dc.subjectAtherosclerosis
dc.subjectHypertension
dc.subjectTachykinins
dc.subjectGuidelines
dc.subjectManagement
dc.subjectReceptors
dc.subjectTissues
dc.titlePlasma urotensin II and neurokinin B levels in acute myocardial infarction and stable coronary artery disease
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
5320.pdf
Boyut:
89.94 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu