The Survivorship Bias in Congenital Diaphragmatic Hernia

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dc.authorscopusid56985532100
dc.authorscopusid57221083929
dc.authorscopusid6701667588
dc.authorscopusid7006112666
dc.authorscopusid7005874031
dc.contributor.authorAydın, Emrah
dc.contributor.authorTorlak, N.
dc.contributor.authorHaberman, B.
dc.contributor.authorLim, F.Y.
dc.contributor.authorPeiro, J.L.
dc.date.accessioned2022-05-11T14:04:53Z
dc.date.available2022-05-11T14:04:53Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Çocuk Cerrahisi Ana Bilim Dalı
dc.description.abstractCurrent literature for congenital diaphragmatic hernia (CDH) focuses on the comparison of the overall mortality in CDH patients. Only a few studies concentrate on analyzing the unstable patients who could not achieve surgical repair, as well as those who could but did not survive after. Hence, this study aimed to analyze the effects of various parameters on the timing of death. A ret-rospective analysis was performed by using the data of all CDH patients from 2003 to 2016 at a single tertiary center. Patients who were diagnosed with left-sided CDH and expired were included in the study regardless of the cause. Of the 66 expired patients, 5 were excluded due to right-sided CDH. The study population constituted a total of 61 patients, of which 31 patients expired prior to CDH repair, and 30 patients expired at different times after CDH repair. Multinomial regression analysis identified that the ECMO need (B = 20.257, p = 0.000, OR: 62.756, 95% CI 10.600–371.384) and O/E LHR (B = 20.376, p = 0.000, OR: 70.663, 95% CI 48.716–102.415) values were the independent predictors that influenced mortality in this cohort. Prenatal pulmonary measurements are the major predictors determining the severity of the disease in patients with CDH. © 2022 by the authors. Li-censee MDPI, Basel, Switzerland.
dc.identifier.doi10.3390/children9020218
dc.identifier.issn2227-9067
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85124231941
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.3390/children9020218
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4828
dc.identifier.volume9
dc.identifier.wosWOS:000763023500001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorAydın, Emrah
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofChildren
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCongenital diaphragmatic hernia
dc.subjectLHR
dc.subjectMortality
dc.subjectO/E LHR
dc.subjectO/E TLV
dc.subjectPostnatal opera-tion
dc.titleThe Survivorship Bias in Congenital Diaphragmatic Hernia
dc.typeArticle

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