The Survivorship Bias in Congenital Diaphragmatic Hernia
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Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI
Access Rights
info:eu-repo/semantics/openAccess
Abstract
Current literature for congenital diaphragmatic hernia (CDH) focuses on the comparison of the overall mortality in CDH patients. Only a few studies concentrate on analyzing the unstable patients who could not achieve surgical repair, as well as those who could but did not survive after. Hence, this study aimed to analyze the effects of various parameters on the timing of death. A ret-rospective analysis was performed by using the data of all CDH patients from 2003 to 2016 at a single tertiary center. Patients who were diagnosed with left-sided CDH and expired were included in the study regardless of the cause. Of the 66 expired patients, 5 were excluded due to right-sided CDH. The study population constituted a total of 61 patients, of which 31 patients expired prior to CDH repair, and 30 patients expired at different times after CDH repair. Multinomial regression analysis identified that the ECMO need (B = 20.257, p = 0.000, OR: 62.756, 95% CI 10.600–371.384) and O/E LHR (B = 20.376, p = 0.000, OR: 70.663, 95% CI 48.716–102.415) values were the independent predictors that influenced mortality in this cohort. Prenatal pulmonary measurements are the major predictors determining the severity of the disease in patients with CDH. © 2022 by the authors. Li-censee MDPI, Basel, Switzerland.
Description
Keywords
Congenital diaphragmatic hernia, LHR, Mortality, O/E LHR, O/E TLV, Postnatal opera-tion
Journal or Series
Children
WoS Q Value
Q2
Scopus Q Value
Q2
Volume
9
Issue
2
