Comparison of Cytotoxic Flow Cytometric Cross Match With Complement Dependent Lymphocytotoxicity and Flow Cytometric Cross Match in Renal Transplant Patients

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dc.authorscopusid9242258800
dc.authorscopusid6506463113
dc.authorscopusid55556291400
dc.authorscopusid8624948000
dc.contributor.authorBilgen, Türker
dc.contributor.authorCanbakan, Mustafa
dc.contributor.authorŞahin, G.
dc.contributor.authorTitiz, Mesut İzzet
dc.date.accessioned2022-05-11T14:02:49Z
dc.date.available2022-05-11T14:02:49Z
dc.date.issued2019
dc.departmentYüksekokullar, Sağlık Yüksekokulu, Beslenme ve Diyetetik Bölümü
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.description.abstractCytotoxic flow cytometric crossmatch (cFCXM), identified by detecting complement-mediated cytotoxic cell death in addition to the capability of showing the alloantibodies binding onto lymphocytes at the same time, can reduce the necessary time and workload in evaluating alloantibodies. More data from clinical samples are needed for cFCXM to be accepted by tissue typing laboratories. In this study, we compared cFCXM with complement-dependent lymphocytotoxicity and standard flow cytometric crossmatch in 41 renal pretransplant patients. A comparison of the obtained data was performed using Spearman's correlation test. We found that cFCXM showed no statistically significant differences with complement-dependent lymphocytotoxicity and flow cytometric crossmatch. We believe that cFCXM can be used in clinical laboratories in the near future following intra-laboratory validation. © 2019 Elsevier Inc.
dc.identifier.doi10.1016/j.transproceed.2019.01.099
dc.identifier.endpage1023
dc.identifier.issn0041-1345
dc.identifier.issue4en_US
dc.identifier.pmid31101163
dc.identifier.scopus2-s2.0-85065578778
dc.identifier.scopusqualityQ3
dc.identifier.startpage1021
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2019.01.099
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4497
dc.identifier.volume51
dc.identifier.wosWOS:000500179300003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBilgen, Türker
dc.institutionauthorTitiz, Mesut İzzet
dc.language.isoen
dc.publisherElsevier USA
dc.relation.ispartofTransplantation Proceedings
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectArticle
dc.subjectblood examination
dc.subjectclinical laboratory
dc.subjectcomplement dependent lymphocytotoxicity
dc.subjectcontrolled study
dc.subjectcorrelation coefficient
dc.subjectcytotoxic flow cytometric crossmatch
dc.subjectcytotoxicity test
dc.subjectflow cytometric crossmatch
dc.subjectflow cytometry
dc.subjectgraft recipient
dc.subjecthuman
dc.subjecthuman cell
dc.subjectintermethod comparison
dc.subjectkidney transplantation
dc.subjectpriority journal
dc.subjectcomparative study
dc.subjectcytotoxicity test
dc.subjectfemale
dc.subjectflow cytometry
dc.subjecthistocompatibility test
dc.subjectimmunology
dc.subjectkidney transplantation
dc.subjectmale
dc.subjectprocedures
dc.subjectalloantibody
dc.subjectCytotoxicity Tests, Immunologic
dc.subjectFemale
dc.subjectFlow Cytometry
dc.subjectHistocompatibility Testing
dc.subjectHumans
dc.subjectIsoantibodies
dc.subjectKidney Transplantation
dc.subjectMale
dc.titleComparison of Cytotoxic Flow Cytometric Cross Match With Complement Dependent Lymphocytotoxicity and Flow Cytometric Cross Match in Renal Transplant Patients
dc.typeArticle

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