Heart rate recovery may predict the presence of coronary artery disease

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dc.authorscopusid16315021800
dc.authorscopusid6505680586
dc.authorscopusid25225280400
dc.authorscopusid55810763400
dc.authorscopusid7005837198
dc.authorwosidAlpsoy, Seref/Z-1808-2018
dc.contributor.authorAkyüz, Aydın
dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorAkkoyun, Dursun Çayan
dc.contributor.authorDeğirmenci, Hasan
dc.contributor.authorGüler, Niyazi
dc.date.accessioned2022-05-11T14:40:08Z
dc.date.available2022-05-11T14:40:08Z
dc.date.issued2014
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractObjective: We investigated whether post-exercise first minute abnormal heart rate recovery (HRR1) helps to predict the presence and severity of CAD, because of some confounding data. Methods: A cross-sectional, retrospective study was performed. Two hundred individuals were included. Gensini scores and the number of coronary artery involvements were used to evaluate the severity of CAD. Student's t-test, Mann-Whitney U test and chi-square test were used for the analysis continuous and categorical data. Spearman's correlation analysis was used to determine whether there is correlation between Gensini scoring and HRR1. Univariate and multivariate logistic regression were used to determine predictors for abnormal HRR1. ROC curve analysis was performed to detect the best sensitivity and specificity value of HRR1 in predicting CAD presence. Results: Seventy subjects (35%) did not have CAD, and CAD was present in 130 patients (65%). HRR1 <= 21 beats with ROC analysis was determined to be the best cut off point. After adjustment between the two groups in terms of age, gender, diabetes, hypertension, dyslipidemia or smoking (all p>0.05), there was relationship CAD presence and abnormal HRR1 (OR=2.1, 95% CI: 1.1-3.9, p=0.02), but not between CAD severity and HRR1 (r=-0.13, p=0.112). The sensitivity, specificity, and the positive and negative predictive values of abnormal HRR1 <= 21 beats at first minute for predicting CAD presence were 76.1%, 41.3% (AUC=0.588, CI 95%: 0.517-0,657, p=0.039), 70.7% and 48.3%, respectively. Conclusion: In the study abnormal HRR1 predicted the presence of CAD, but not the severity of it.
dc.identifier.doi10.5152/akd.2014.4824
dc.identifier.endpage356
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue4en_US
dc.identifier.pmid24818624
dc.identifier.scopus2-s2.0-84903139645
dc.identifier.scopusqualityQ3
dc.identifier.startpage351
dc.identifier.urihttps://doi.org/10.5152/akd.2014.4824
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8875
dc.identifier.volume14
dc.identifier.wosWOS:000338109400010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAkyüz, Aydın
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorAkkoyun, Dursun Çayan
dc.institutionauthorDeğirmenci, Hasan
dc.institutionauthorGüler, Niyazi
dc.language.isoen
dc.publisherAves
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectheart rate recovery
dc.subjectcoronary artery disease
dc.subjectregression analysis
dc.subjectdiagnostic accuracy
dc.subjectsensitivity
dc.subjectspecificity
dc.subjectVentricular Systolic Dysfunction
dc.subjectChronotropic Response
dc.subjectTreadmill Exercise
dc.subjectMortality
dc.subjectSeverity
dc.titleHeart rate recovery may predict the presence of coronary artery disease
dc.typeArticle

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