Peripheral Blood CD34+ Cell Counts in Patients With Severe Sepsis

dc.authorid0000-0002-0920-6895
dc.authorscopusid35271464000
dc.authorscopusid23004514700
dc.authorscopusid6602098737
dc.authorscopusid6603662687
dc.authorscopusid6603864022
dc.authorscopusid56444012900
dc.authorscopusid37101026900
dc.authorwosidkelestimur, f/ABE-9873-2021
dc.authorwosidKaraca, Züleyha/ABB-7891-2021
dc.authorwosidElbuken, Gulsah/ABD-5689-2020
dc.contributor.authorElbüken, Gülşah
dc.contributor.authorKaraca, Züleyha
dc.contributor.authorTanriverdi, Fatih
dc.contributor.authorEser, Bülent
dc.contributor.authorÜnlühızarcı, Kursad
dc.contributor.authorCoşkun, Ramazan
dc.contributor.authorKelestimur, Fahrettin
dc.date.accessioned2022-05-11T14:39:54Z
dc.date.available2022-05-11T14:39:54Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractObjectives: This study aims to determine the impact of severe sepsis (SS) on CD34(+) cell counts in the peripheral blood and to compare these counts with those of healthy subjects. Patients and methods: CD34(+) cell counts in the peripheral blood were measured in 20 patients with SS (12 males, 8 females; mean age 58.6 +/- 16.3 years; range 23 to 81 years) (group 1) and 32 healthy subjects (16 males, 16 females; mean age 51.8 +/- 8.6 years; range 36 to 64 years) (group 2). Blood samples were obtained from group 1 two times on second day (D2) within the first 24-48 hours and on seventh day (D7) after diagnosis and once from group 2 on their first day of admittance. Results: In group 1, CD34(+) cell counts on D2 were lower than those on D7, but the difference was not statistically significant. Neither on D2 nor on D7 CD34(+) cell counts of group 1 were different than those in group 2. Although CD34(+) cell counts in group 1 on D7 were higher than those of group 2, the difference was not statistically significant. CD34(+) cell counts did not differ according to the presence of adrenal insufficiency (AI) or survival status. Conclusion: Overall CD34(+) cell counts of SS patients were not different from those in healthy subjects and not affected by the presence of AI or survival in the SS group.
dc.description.sponsorshipErciyes University Council of Scientific InvestigationsErciyes University [TSA-10-2905]
dc.description.sponsorshipGrant support was provided by Erciyes University Council of Scientific Investigations (Project code: TSA-10-2905).
dc.identifier.doi10.5606/tji.2016.481
dc.identifier.endpage24
dc.identifier.issn1301-109X
dc.identifier.issn2147-8325
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84992623480
dc.identifier.scopusqualityQ4
dc.identifier.startpage19
dc.identifier.urihttps://doi.org/10.5606/tji.2016.481
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8790
dc.identifier.volume4
dc.identifier.wosWOS:000395317600001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorElbüken, Gülşah
dc.language.isoen
dc.publisherTurkish Soc Immunology
dc.relation.ispartofTurkish Journal of Immunology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCD34
dc.subjecthealthy group
dc.subjecthematopoietic stem cell
dc.subjectsevere sepsis
dc.subjectEndothelial Progenitor Cells
dc.subjectStem-Cells
dc.titlePeripheral Blood CD34+ Cell Counts in Patients With Severe Sepsis
dc.title.alternativeAğır sepsisli hastalarda periferik kan CD34+ hücre sayıları]
dc.typeArticle

Dosyalar