Fabrication of Electrochemical Immunosensor for Detection of Interleukin 8 Biomarker via Layer-by-layer Self-assembly Process on Cost-effective Fluorine Tin Oxide Electrode

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dc.authorscopusid57194273220
dc.authorscopusid6506764918
dc.contributor.authorAydın, Elif Burcu
dc.contributor.authorSezgintürk, Mustafa Kemal
dc.date.accessioned2022-05-11T14:07:25Z
dc.date.available2022-05-11T14:07:25Z
dc.date.issued2021
dc.departmentRektörlüğe Bağlı Bölümler, Rektörlük, Bilimsel ve Teknolojik Araştırmalar Uygulama ve Araştırma Merkezi
dc.description.abstractA highly sensitive impedimetric immunosensor for the determination of interleukin 8 (IL 8) cancer biomarker was fabricated via simple fabrication process. A silane agent with isocyanate groups, 3-(triethoxysilyl)propyl isocyanate (IPTES), were utilized for binding of IL 8 antigen specific antibodies and self-assembled on the fluorine tin oxide (FTO) substrate with a standard silanization chemistry. Under optimum experimental conditions, the designed immunosensor had a wide linear detection range of 0.02–4 pg/mL, a low limit of detection of 11.9 fg/mL and a high sensitivity of 4.42 k? pg?1 mL cm?2. The designed biosensor displayed high reproducibility and repeatability, good selectivity against interference biomarkers. © 2021 Wiley-VCH GmbH
dc.identifier.doi10.1002/elan.202060603
dc.identifier.endpage1605
dc.identifier.issn1040-0397
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85102957235
dc.identifier.scopusqualityQ2
dc.identifier.startpage1596
dc.identifier.urihttps://doi.org/10.1002/elan.202060603
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5100
dc.identifier.volume33
dc.identifier.wosWOS:000631854300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorAydın, Elif Burcu
dc.language.isoen
dc.publisherJohn Wiley and Sons Inc
dc.relation.ispartofElectroanalysis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subject3-(triethoxysilyl)propyl isocyanate
dc.subjectDisposable electrode
dc.subjectFluorine tin oxide
dc.subjectInterleukin 8
dc.titleFabrication of Electrochemical Immunosensor for Detection of Interleukin 8 Biomarker via Layer-by-layer Self-assembly Process on Cost-effective Fluorine Tin Oxide Electrode
dc.typeArticle

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