The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health

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dc.authorscopusid57209908947
dc.authorscopusid55921065100
dc.contributor.authorAsmaz, E.D.
dc.contributor.authorSeyidoğlu, Nilay
dc.date.accessioned2023-04-20T08:05:54Z
dc.date.available2023-04-20T08:05:54Z
dc.date.issued2022
dc.departmentFakülteler, Veteriner Fakültesi, Temel Bilimler Bölümü, Fizyoloji Ana Bilim Dalı
dc.description.abstractSpirulina is a popular herbal food that has a preventive effect on health. In the study, it aimed to evaluate the effects of different doses of Spirulina platensis (Arthrospira platensis) on the morphological properties of the duodenum of rats, and to assign the effect of Spirulina on the expression of proliferating cell nuclear antigen (PCNA) in the rat duodenum, and thereby to observe the effects on intestinal health. 30 male Wistar albino rats were divided into 3 groups for 45 days. The first group was received the basal diet; the second group was given 500 mg/kg Spirulina daily by oral gavage; the third group was given 1000 mg/kg Spirulina daily. The duodenum segments were taken at the end of the trial and processed for histological assay. Although the total mucosa, villus height and villus/cript ratio were found higher in high dose Spirulina, the lower cript depth was detected in same group compared to control and low dose group. A significant increase was observed at high dose compared to the control and low dose group in terms of PCNA expression intensity and proliferation index. Findings suggest that high dose of Spirulina may support the duodenal growth, and thereby intestinal health. © 2022
dc.description.sponsorship16,074
dc.description.sponsorshipSpecial thanks to Prof. Dr. Berrin Zik for scientific advances and assistance during research. This study was supported by grant from the Research Foundations of University (NKUBAP.10.GA.16.074).
dc.identifier.doi10.1016/j.fshw.2022.04.027
dc.identifier.endpage1346
dc.identifier.issn2213-4530
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85132398750
dc.identifier.scopusqualityQ1
dc.identifier.startpage1342
dc.identifier.urihttps://doi.org/10.1016/j.fshw.2022.04.027
dc.identifier.urihttps://hdl.handle.net/20.500.11776/11089
dc.identifier.volume11
dc.indekslendigikaynakScopus
dc.institutionauthorSeyidoğlu, Nilay
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofFood Science and Human Wellness
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDuodenum
dc.subjectHistochemistry
dc.subjectIntestinal health
dc.subjectSpirulina platensis
dc.titleThe prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health
dc.typeArticle

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